Rhodium-catalyzed hydroformylation of alkynes employing a self-assembling ligand system

被引：65

作者：

Agabekov, Vladislav ^{[1
]}

Seiche, Wolfgang ^{[1
]}

Breit, Bernhard ^{[1
]}

机构：

[1] Univ Freiburg, Inst Organ Chem, D-79104 Freiburg, Germany

来源：

CHEMICAL SCIENCE | 2013年 / 4卷 / 06期

关键词：

COMBINATORIAL HOMOGENEOUS CATALYSIS; REGIOSELECTIVE HYDROFORMYLATION; BIDENTATE LIGANDS; TRIPHENYL PHOSPHITE; TERMINAL ALKENES; METAL CATALYSIS; BASE-PAIR; COMPLEX; ORGANOCATALYSIS; CONSTRUCTION;

D O I：

10.1039/c3sc50725d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Hydroformylation of alkynes is an underdeveloped atom-economic and redox-neutral method to prepare enals. Applying a new electron poor self-assembling ligand system provides the first general rhodium-catalyst for the chemo- and stereoselective hydroformylation of dialkyl- as well as diaryl-substituted alkynes to furnish enals in excellent chemo- and stereoselectivity.

引用

页码：2418 / 2422

页数：5

共 55 条

[1] Domino hydroformylation/enantioselective cross-aldol addition [J].

Abillard, Olivier ;

Breit, Bernhard .

ADVANCED SYNTHESIS & CATALYSIS, 2007, 349 (11-12) :1891-1895

[2]

[Anonymous], 2007, ANGEW CHEM

[3]

Bausch C.C., 2011, ANGEW CHEM INT EDIT, V123, P5805

[4] Divergent Regioselectivity in the Synthesis of Trisubstituted Allylic Alcohols by Nickel- and Ruthenium-Catalyzed Alkyne Hydrohydroxymethylation with Formaldehyde [J].

Bausch, Cory C. ;

Patman, Ryan L. ;

Breit, Bernhard ;

Krische, Michael J. .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2011, 50 (25) :5686-5689

[5]

Botteghi C., 1974, TETRAHEDRON LETT, V15, P4285

[6] Supramolecular approaches to generate libraries of chelating bidentate ligands for homogeneous catalysis [J].

Breit, B .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2005, 44 (42) :6816-6825

[7] Self-assembly of bidentate ligands for combinatorial homogeneous catalysis based on an A-T base-pair model [J].

Breit, B ;

Seiche, W .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2005, 44 (11) :1640-1643

[8] Hydrogen bonding as a construction element for bidentate donor ligands in homogeneous catalysis: Regioselective hydroformylation of terminal alkenes [J].

Breit, B ;

Seiche, W .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2003, 125 (22) :6608-6609

[9]

Breit B, 2001, SYNTHESIS-STUTTGART, P1

[10]

Breit B, 2001, ANGEW CHEM INT EDIT, V40, P1910, DOI 10.1002/1521-3773(20010518)40:10<1910::AID-ANIE1910>3.3.CO

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