Assessment of a commercial sandwich ELISA in the diagnosis of aspergillosis in falcons

被引：21

作者：

Arca-Ruibal, B

Wernery, U

Zachariah, R

Bailey, TA

Di Somma, A

Silvanose, C

McKinney, P

机构：

[1] Wildlife Protect Off, Al Wasl Vet Clin, Dubai, U Arab Emirates

[2] Dubai Falcon Hosp, Dubai, U Arab Emirates

[3] Cent Vet Res Lab, Dubai, U Arab Emirates

来源：

VETERINARY RECORD | 2006年 / 158卷 / 13期

关键词：

D O I：

10.1136/vr.158.13.442

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

A commercial sandwich ELISA (Platelia Aspergillus EIA; Bio-Rad) developed for the detection of galactomannan, a major cell wall constituent of Aspergillus species, was tested for its efficacy in the diagnosis of aspergillosis in falcons. Ninety serum samples from 50 aspergillosis-positive falcons and 182 samples from 142 aspergillosis-negative falcons were tested. The sensitivity of the test was only 12 per cent and its specificity was 95 per cent. The test was therefore unsatisfactory for detecting galactomannan in the serum samples and cannot be used as a screening test for aspergillosis in falcons.

引用

页码：442 / 444

页数：3

共 24 条

[1] Defining opportunistic invasive fungal infections in immunocompromised patients with cancer and hematopoietic stem cell transplants: An international consensus [J].

Ascioglu, S ;

Rex, JH ;

de Pauw, B ;

Bennett, JE ;

Bille, J ;

Crokaert, F ;

Denning, DW ;

Donnelly, JP ;

Edwards, JE ;

Erjavec, Z ;

Fiere, D ;

Lortholary, O ;

Maertens, J ;

Meis, JF ;

Patterson, TF ;

Ritter, J ;

Selleslag, D ;

Shah, PM ;

Stevens, DA ;

Walsh, TJ .

CLINICAL INFECTIOUS DISEASES, 2002, 34 (01) :7-14

[2]

Baumgartner R., 1988, Proceedings of the 1988 Annual Meeting of the Association of Avian Veterinarians, Houston, Texas, September 27-October 1, 1988., P61

[3] Quantitative galactomannan detection is superior to PCR in diagnosing and monitoring invasive pulmonary aspergillosis in an experimental rat model [J].