With the rapid development of cooperation between countries, as the most basic way of communication, foreign trade oral English becomes more and more important in international trade activities. Because of the difference in mode of thinking and habit of representation between Chinese and Western, as well as the interference of mother-tongue, the cause of oral communication barriers in business English make successful transaction is becoming more and more difficult. First of all, the paper introduces the present situation of oral communication barriers in business. Secondly, from the imperfection of Chinese education, the lack of language environment, the different culture between Chinese and Western countries, and the personal problem of learners to expound the causes of obstacles, and finally, based on the causes of the barriers, analysis the coping strategies.