Challenges to the Treatment and New Perspectives for the Eradication of Helicobacter pylori

被引：15

作者：

Yazbek, Priscila Baptistella ^{[1
]}

Trindade, Ariane Biolcati ^{[1
]}

Chin, Chung Man ^{[1
]}

dos Santos, Jean Leandro ^{[1
]}

机构：

[1] State Univ Sao Paulo Julio de Mesquita Filho, Drugs & Med Dept, Sch Pharmaceut Sci, BR-14801902 Araraquara, SP, Brazil

来源：

DIGESTIVE DISEASES AND SCIENCES | 2015年 / 60卷 / 10期

关键词：

Helicobacter pylori; Treatment; H. pylori resistance; H. pylori eradication; Gastric diseases; CONTAINING TRIPLE THERAPY; RIFAXIMIN-BASED REGIMENS; IN-VITRO; RESCUE THERAPY; SEQUENTIAL THERAPY; ANTIBIOTIC-RESISTANCE; ENHANCES PROTECTION; GLYCYRRHIZA-GLABRA; QUADRUPLE THERAPY; INDUCED GASTRITIS;

D O I：

10.1007/s10620-015-3712-y

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Helicobacter pylori (H. pylori) is one of the leading causes of gastric diseases such as chronic gastritis, peptic ulcer, and gastric adenocarcinoma. The current treatment of H. pylori infection with antibiotics and proton pump inhibitors has several limitations, including poor adherence and intrinsic patient-related factors, drug resistance, and the absence of adequate treatments. This review summarizes the current therapeutic approaches to eradicating H. pylori, the difficulties associated with its treatment, and several new perspectives aimed at improving existing treatment strategies.

引用

页码：2901 / 2912

页数：12

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