One-pot synthesis of β- and γ-aminofunctionalised amines and silanes via hydroaminomethylation of enamines and vinylsilanes

被引：15

作者：

Bärfacker, L ^{[1
]}

Rische, T ^{[1
]}

Eilbracht, P ^{[1
]}

机构：

[1] Univ Dortmund, D-44221 Dortmund, Germany

来源：

TETRAHEDRON | 1999年 / 55卷 / 23期

关键词：

hydroaminomethylation; rhodium(I)-catalysis; beta- and gamma-aminofunctionalised amines; enamines; vinylsilanes;

D O I：

10.1016/S0040-4020(99)00350-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Heterofunctionalised enamines and vinylsilanes under hydroformylation conditions in the presence of primary or secondary amines are converted to form diamines or aminosilanes in one step. This selective one-pot hydroaminomethylation procedure establishes an easy and convenient access to beta- and gamma-aminofunctionalised amines and silanes with potential biological activity. (C) 1999 Elsevier Science Ltd. All rights reserved.

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页码：7177 / 7190

页数：14

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