As a result of the aging US population and the subsequent increase in the prevalence of coronary disease and atrial fibrillation, therapeutic use of anticoagulants has increased. Perioperative and periprocedural management of anticoagulated patients has become routine for anesthesiologists, who frequently mediate communication between the prescribing physician and the surgeon and assess the risks of both thromboembolic complications and hemorrhage. Data from randomized clinical trials on perioperative management of antithrombotic therapy are lacking. Therefore, clinical judgment is typically needed regarding decisions to continue, discontinue, bridge, or resume anticoagulation and regarding the time points when these events should occur in the perioperative period. In this review, we will discuss the most commonly used anticoagulants used in outpatient settings and discuss their management in the perioperative period. Special considerations for regional anesthesia and interventional pain procedures will also be reviewed. (C) 2016 Elsevier Inc. All rights reserved.
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Univ Birmingham, City Hosp, Ctr Cardiovasc Sci, Birmingham B18 7QH, W Midlands, EnglandUniv Birmingham, City Hosp, Ctr Cardiovasc Sci, Birmingham B18 7QH, W Midlands, England
Apostolakis, Stavros
;
Lane, Deirdre A.
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Univ Birmingham, City Hosp, Ctr Cardiovasc Sci, Birmingham B18 7QH, W Midlands, EnglandUniv Birmingham, City Hosp, Ctr Cardiovasc Sci, Birmingham B18 7QH, W Midlands, England
Lane, Deirdre A.
;
Buller, Harry
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Univ Amsterdam, Acad Med Ctr, Dept Vasc Med, NL-1105 AZ Amsterdam, NetherlandsUniv Birmingham, City Hosp, Ctr Cardiovasc Sci, Birmingham B18 7QH, W Midlands, England
Buller, Harry
;
Lip, Gregory Y. H.
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Univ Birmingham, City Hosp, Ctr Cardiovasc Sci, Birmingham B18 7QH, W Midlands, EnglandUniv Birmingham, City Hosp, Ctr Cardiovasc Sci, Birmingham B18 7QH, W Midlands, England
机构:
Mayo Clin, Div Gastroenterol & Hepatol, Rochester, MN 55905 USAMayo Clin, Div Gastroenterol & Hepatol, Rochester, MN 55905 USA
Baron, Todd H.
;
Kamath, Patrick S.
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Mayo Clin, Div Gastroenterol & Hepatol, Rochester, MN 55905 USAMayo Clin, Div Gastroenterol & Hepatol, Rochester, MN 55905 USA
Kamath, Patrick S.
;
McBane, Robert D.
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Mayo Clin, Div Cardiovasc Dis, Rochester, MN 55905 USA
Mayo Clin, Div Hematol, Rochester, MN 55905 USAMayo Clin, Div Gastroenterol & Hepatol, Rochester, MN 55905 USA
机构:
CHI St Lukes Hlth, Baylor St Lukes Med Ctr, Dept Pathol, Houston, TX 77030 USACHI St Lukes Hlth, Baylor St Lukes Med Ctr, Dept Pathol, Houston, TX 77030 USA
机构:
Univ Birmingham, City Hosp, Ctr Cardiovasc Sci, Birmingham B18 7QH, W Midlands, EnglandUniv Birmingham, City Hosp, Ctr Cardiovasc Sci, Birmingham B18 7QH, W Midlands, England
Apostolakis, Stavros
;
Lane, Deirdre A.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Birmingham, City Hosp, Ctr Cardiovasc Sci, Birmingham B18 7QH, W Midlands, EnglandUniv Birmingham, City Hosp, Ctr Cardiovasc Sci, Birmingham B18 7QH, W Midlands, England
Lane, Deirdre A.
;
Buller, Harry
论文数: 0引用数: 0
h-index: 0
机构:
Univ Amsterdam, Acad Med Ctr, Dept Vasc Med, NL-1105 AZ Amsterdam, NetherlandsUniv Birmingham, City Hosp, Ctr Cardiovasc Sci, Birmingham B18 7QH, W Midlands, England
Buller, Harry
;
Lip, Gregory Y. H.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Birmingham, City Hosp, Ctr Cardiovasc Sci, Birmingham B18 7QH, W Midlands, EnglandUniv Birmingham, City Hosp, Ctr Cardiovasc Sci, Birmingham B18 7QH, W Midlands, England
机构:
Mayo Clin, Div Gastroenterol & Hepatol, Rochester, MN 55905 USAMayo Clin, Div Gastroenterol & Hepatol, Rochester, MN 55905 USA
Baron, Todd H.
;
Kamath, Patrick S.
论文数: 0引用数: 0
h-index: 0
机构:
Mayo Clin, Div Gastroenterol & Hepatol, Rochester, MN 55905 USAMayo Clin, Div Gastroenterol & Hepatol, Rochester, MN 55905 USA
Kamath, Patrick S.
;
McBane, Robert D.
论文数: 0引用数: 0
h-index: 0
机构:
Mayo Clin, Div Cardiovasc Dis, Rochester, MN 55905 USA
Mayo Clin, Div Hematol, Rochester, MN 55905 USAMayo Clin, Div Gastroenterol & Hepatol, Rochester, MN 55905 USA
机构:
CHI St Lukes Hlth, Baylor St Lukes Med Ctr, Dept Pathol, Houston, TX 77030 USACHI St Lukes Hlth, Baylor St Lukes Med Ctr, Dept Pathol, Houston, TX 77030 USA