The role of mechanics in biological and bio-inspired systems

被引：191

作者：

Egan, Paul ^{[1
]}

Sinko, Robert ^{[2
]}

LeDuc, Philip R. ^{[1
]}

Keten, Sinan ^{[2
]}

机构：

[1] Carnegie Mellon Univ, Dept Mech Engn Biomed Engn Computat Biol & Biol S, Pittsburgh, PA 15213 USA

[2] Northwestern Univ, Dept Civil & Environm Engn, Dept Mech Engn, Evanston, IL 60208 USA

来源：

NATURE COMMUNICATIONS | 2015年 / 6卷

基金：

美国国家科学基金会;

关键词：

RESILIN-BASED MATERIALS; MOLECULAR-MECHANICS; FRACTURE-TOUGHNESS; FORCE GENERATION; CELL MECHANICS; TISSUE; PROTEIN; FILMS; BIOMECHANICS; COMPOSITES;

D O I：

10.1038/ncomms8418

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Natural systems frequently exploit intricate multiscale and multiphasic structures to achieve functionalities beyond those of man-made systems. Although understanding the chemical make-up of these systems is essential, the passive and active mechanics within biological systems are crucial when considering the many natural systems that achieve advanced properties, such as high strength-to-weight ratios and stimuli-responsive adaptability. Discovering how and why biological systems attain these desirable mechanical functionalities often reveals principles that inform new synthetic designs based on biological systems. Such approaches have traditionally found success in medical applications, and are now informing breakthroughs in diverse frontiers of science and engineering.

引用

页数：12

共 110 条

[1] Hierarchies, multiple energy barriers, and robustness govern the fracture mechanics of α-helical and β-sheet protein domains [J].