Intramolecular Mannich reaction of 2-oxotryptamines with acetone yielding spiro[indole-3,3′-pyrrolidin]-2-ones

被引：4

作者：

Incze, M ^{[1
]}

Dörnyei, G ^{[1
]}

Kajtár-Peredy, M ^{[1
]}

Szántay, C ^{[1
]}

机构：

[1] Hungarian Acad Sci, Inst Chem, Chem Res Ctr, H-1025 Budapest 2, Hungary

来源：

COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS | 1999年 / 64卷 / 02期

关键词：

intramolecular Mannich reaction; spirocyclic compounds; indoles; pyrrolidines; cyclizations; alkaloids;

D O I：

10.1135/cccc19990408

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

2-Oxotryptamines undergo intramolecular Mannich-type cyclization with acetone to give 2',2'-dimethylspiro[indole-3,3'-pyrrolidin]-2-ones. In presence of an alkylating reagent, this reaction gives the corresponding 1'-substituted products.

引用

页码：408 / 416

页数：9

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