Extranodal follicular lymphoma in the lung of a free-ranging red deer (Cervus elaphus)

被引:2
作者
Chang Reissig, Elizabeth [1 ]
Valli, Victor E. [2 ]
Pesavento, Patricia [3 ]
Massone, Adriana R. [1 ]
Iovanitti, Beatriz [4 ]
Gimeno, Eduardo J. [1 ]
Uzal, Francisco A. [5 ]
机构
[1] Natl Univ La Plata, Inst Pathol, Fac Vet Sci, La Plata, Buenos Aires, Argentina
[2] Vdx Vet Pathol Serv, Davis, CA USA
[3] Univ Calif Davis, Sch Vet Med, Dept Pathol Microbiol & Immunol, Davis, CA 95616 USA
[4] Natl Serv Hlth & Agroalimentary Qual, San Carlos De Bariloche, Rio Negro, Argentina
[5] Calif State Univ San Bernardino, San Bernardino Branch, Sch Vet Med, Calif Anim Hlth & Food Safety Lab Syst, San Bernardino, CA 92407 USA
关键词
Cluster of differentiation (CD)3; CD20; follicular lymphoma; immunohistochemistry; red deer;
D O I
10.1177/1040638712467987
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
A hunted free-ranging female red deer (Cervus elaphus) from a region near the Nahuel Huapi National Park, Northern Patagonia, Argentina, had a focally extensive peribronchial lymphoid proliferative lesion in the lung characterized by formation of multiple follicles, with prominent germinal centers lacking mantle zone cells and antigen-related polarity. On examination of immunohistochemically stained tissues, a predominance of B cells (cluster of differentiation [CD]20 positive) with only a few scattered T cells (CD3 positive) were present. The histologic and immunohistochemical characteristics are consistent with follicular lymphoma, which is frequently seen in human beings and less frequently in domestic animals.
引用
收藏
页码:158 / 161
页数:4
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