Thymocyte differentiation: it's time to bend a little

被引:4
作者
Kioussis, D [1 ]
机构
[1] Natl Inst Med Res, Div Mol Immunol, London NW7 1AA, England
关键词
D O I
10.1038/ni0302-214
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The development of new experimental tools is helping to unravel the molecular secrets of cell differentiation. The identification, by gene chip technology, of a HMG box protein called TOX has yielded valuable information about thymocyte differentiation.
引用
收藏
页码:214 / 215
页数:2
相关论文
共 12 条
[1]   The CD4/CD8 lineage decision: integration of signalling pathways [J].
Basson, MA ;
Zamoyska, R .
IMMUNOLOGY TODAY, 2000, 21 (10) :509-514
[2]   The regulation of CD4 and CD8 coreceptor gene expression during T cell development [J].
Ellmeier, W ;
Sawada, S ;
Littman, DR .
ANNUAL REVIEW OF IMMUNOLOGY, 1999, 17 :523-554
[3]  
GODFREY DI, 1993, J IMMUNOL, V150, P4244
[4]   Hierarchical interactions of control elements determine CD8α gene expression in subsets of thymocytes and peripheral T cells [J].
Hostert, A ;
Garefalaki, A ;
Mavria, G ;
Tolaini, M ;
Roderick, K ;
Norton, T ;
Mee, PJ ;
Tybulewicz, VLJ ;
Coles, M ;
Kioussis, D .
IMMUNITY, 1998, 9 (04) :497-508
[5]   Regulation of IL-4 gene expression by distal regulatory elements and GATA-3 at the chromatin level [J].
Lee, GR ;
Fields, PE ;
Flavell, RA .
IMMUNITY, 2001, 14 (04) :447-459
[6]   Bridging the NFAT and NF-κB families:: NFAT5 dimerization regulates cytokine gene transcription in response to osmotic stress [J].
López-Rodríguez, C ;
Aramburu, J ;
Jin, L ;
Rakeman, AS ;
Michino, M ;
Rao, A .
IMMUNITY, 2001, 15 (01) :47-58
[7]   Control of lymphocyte differentiation by the LEF-1/TCF family of transcription factors [J].
Reya, T ;
Okamura, R ;
Grosschedl, R .
COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY, 1999, 64 :133-140
[8]   SELECTIVE EVENTS IN T-CELL DEVELOPMENT [J].
ROBEY, E ;
FOWLKES, BJ .
ANNUAL REVIEW OF IMMUNOLOGY, 1994, 12 :675-705
[9]   Autonomous maturation of α/β T lineage cells in the absence of COOH-terminal Src kinase (Csk) [J].
Schmedt, C ;
Tarakhovsky, A .
JOURNAL OF EXPERIMENTAL MEDICINE, 2001, 193 (07) :815-825
[10]   Transcriptional control of T lymphocyte differentiation [J].
Staal, FJT ;
Weerkamp, F ;
Langerak, AW ;
Hendriks, RW ;
Clevers, HC .
STEM CELLS, 2001, 19 (03) :165-179