Occupational contact dermatitis in painters - an analysis of patch test data from the Danish Contact Dermatitis Group

被引:47
作者
Mose, Anja P. [1 ]
Lundov, Michael D. [1 ]
Zachariae, Claus
Menne, Torkil
Veien, Niels K. [2 ]
Laurberg, Grete [2 ]
Kaaber, Knud [3 ]
Avnstorp, Christian [4 ]
Andersen, Klaus E. [5 ,6 ]
Paulsen, Evy [5 ,6 ]
Mortz, Charlotte G. [5 ,6 ]
Sommerlund, Mette [7 ]
Danielsen, Anne [8 ]
Thormann, Jens [9 ]
Kristensen, Ove [10 ]
Kristensen, Berit [10 ]
Andersen, Bo L. [11 ]
Vissing, Susanne [12 ]
Nielsen, Niels H. [13 ]
Johansen, Jeanne D. [1 ]
机构
[1] Univ Hosp Copenhagen Gentofte, Dept Dermatoallergol, Natl Allergy Res Ctr, DK-2900 Hellerup, Denmark
[2] Dermatol Clin, DK-9000 Aalborg, Denmark
[3] Dermatol Clin, DK-7400 Herning, Denmark
[4] Dermatol Clin, DK-2610 Rodovre, Denmark
[5] Odense Univ Hosp, Dept Dermatol, DK-5000 Odense, Denmark
[6] Odense Univ Hosp, Allergy Unit, DK-5000 Odense, Denmark
[7] Arhus Univ Hosp, Dept Dermatol, Aarhus, Denmark
[8] Dermatol Clin, DK-1570 Copenhagen, Denmark
[9] Dermatol Clin, DK-7100 Vejle, Denmark
[10] Dermatol Clin, DK-4400 Kalundborg, Denmark
[11] Dermatol Clin, DK-5700 Svendborg, Denmark
[12] Dermatol Clin, DK-2970 Horsholm, Denmark
[13] Dermatol Clin, DK-2880 Bagsvaerd, Denmark
关键词
allergens; contact dermatitis; epoxy resin; hand eczema; methylchloroisothiazolinone; methylisothiazolinone; occupation; painters; preservatives; SKIN-DISEASE; EXPOSURE; ALLERGY; FORMALDEHYDE; DERMATOSES; SYMPTOMS;
D O I
10.1111/j.1600-0536.2012.02074.x
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Background. Painters are among the occupational groups that most commonly experience occupational contact dermatitis, but few investigations exist concerning this occupation. Objectives. To characterize painters with contact dermatitis and identify the most common allergens associated with the occupation. Materials and methods. All patch test results of 219 painters and 1095 matched controls registered by the Danish Contact Dermatitis Group between 2001 and 2010 were analysed. Results. Hand eczema (p < 0.0001) and occupational contact dermatitis (p < 0.0001) were observed significantly more often in the painters than in the group of controls. Sensitizations to the following allergens from the European baseline series were associated with the occupation and were statistically significant: methylchloroisothiazolinone/methylisothiazolinone, epoxy resin, formaldehyde, and quaternium-15. Three different isothiazolinones emerged as the most frequent sensitizers of the allergens tested in addition to the baseline series. Conclusions. The results indicate that painters have an increased risk of developing occupational hand eczema. Isothiazolinones and epoxy resin proved to be the two most frequent sensitizers in painters.
引用
收藏
页码:293 / 297
页数:5
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