Background: The purpose of this study was to measure the relationship between various determinant variables and cyberbullying behavior among youth in Jakarta, Indonesia. Six determinant variables were examined including perceived social support factors (social support from family and friends), cyber factors (problematic Internet use and time spent online), and psychological factors (attitude toward cyberbullying and self-esteem). The results of this study can be used to make recommendations to the government or related organizations about cyberbullying issues. Methods: This study used a questionnaire as the data collecting instrument. A total of 210 young people participated in this study. Pearson product moment correlations were used to measure the relationship between the determinant variables and the likelihood of cyberbullying, and multiple linear regression was used to identify the factors related with cyberbullying. Results: From six determinant variables, we found that five were related with cyberbullying behavior. Social support from friends was found to have the strongest relationship with cyberbullying behavior. Self-esteem, social support from family, attitude toward cyberbullying, and problematic Internet use were also found to be related with cyberbullying behavior. Conclusions: There were significant relationships between cyberbullying behavior and four determinant variables. The strongest was social support from friends followed by self-esteem, social support from family, attitude toward cyberbullying, and problematic Internet use.