Study on surface modification of porous apatite-wollastonite bioactive glass ceramic scaffold

被引：16

作者：

Cao, Bin ^{[1
]}

Zhou, Dali ^{[1
]}

Xue, Ming ^{[1
]}

Li, Guangda ^{[1
]}

Yang, Weizhong ^{[1
]}

Long, Qin ^{[1
]}

Ji, Li ^{[1
]}

机构：

[1] Sichuan Univ, Coll Mat Sci & Engn, Chengdu 610064, Peoples R China

来源：

APPLIED SURFACE SCIENCE | 2008年 / 255卷 / 02期

关键词：

Apatite-wollastonite glass ceramic (AW GC); Chitosan (CS); Surface modification; Bone tissue engineering; Bioactive glass ceramic; Scaffold;

D O I：

10.1016/j.apsusc.2008.06.066

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Chitosan (CS) was used to modify the surface of apatite-wollastonite bioactive glass ceramic (AW GC) scaffold to prepare AW/CS composite scaffold. The in vitro bioactivity of the AW/CS composite scaffold was investigated by simulated body fluid (SBF) soaking experiment. Cell growth on the surface of the material was evaluated by co-culturing osteogenic marrow stromal cells (MSCs) of rabbits with the scaffold. The results showed that the compressive strength of AW GC scaffold was improved dramatically after being modified by CS, whereas the mineralization rate was delayed. MSCs can attach well on the surface of the composite scaffold. (C) 2008 Elsevier B.V. All rights reserved.

引用

页码：505 / 508

页数：4

共 7 条

[1]

CHAN TMY, 1995, PROCEEDINGS OF THE SIXTH ANNUAL ACM-SIAM SYMPOSIUM ON DISCRETE ALGORITHMS, P282, DOI 10.1109/SBEC.1995.514502

[2]

Hu QL, 2001, CHINESE J POLYM SCI, V19, P467

[3] SOLUTIONS ABLE TO REPRODUCE INVIVO SURFACE-STRUCTURE CHANGES IN BIOACTIVE GLASS-CERAMIC A-W3 [J].

KOKUBO, T ;

KUSHITANI, H ;

SAKKA, S ;

KITSUGI, T ;

YAMAMURO, T .

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, 1990, 24 (06) :721-734

[4]

WANG SB, 1999, J HUAQIAO U, V20, P407

[5]

Xue M, 2007, CHINESE J INORG CHEM, V23, P708

[6] Preparation and in vitro investigation of chitosan/nano-hydroxyapatite composite used as bone substitute materials [J].

Zhang, L ;

Li, YB ;

Yang, AP ;

Peng, XL ;

Wang, XJ ;

Zhang, X .

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 2005, 16 (03) :213-219

[7]

[赵宝林 Zhao Baolin], 2003, [医用生物力学, Journal of medical biomechanics], V18, P234

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