Chiral resolution of the dansyl derivative of 2-methyltaurine by capillary electrophoresis

被引：11

作者：

Anselmi, S

Braghiroli, D

DiBella, M

Schmid, MG

Wintersteiger, R

Gubitz, G

机构：

[1] UNIV MODENA,DIPARTIMENTO SCI FARMACEUT,I-41100 MODENA,ITALY

[2] KARL FRANZENS UNIV GRAZ,INST PHARMAZEUT CHEM,A-8010 GRAZ,AUSTRIA

来源：

JOURNAL OF CHROMATOGRAPHY B-BIOMEDICAL APPLICATIONS | 1996年 / 681卷 / 01期

关键词：

enantiomer separation; 2-methyltaurine; taurine;

D O I：

10.1016/0378-4347(95)00532-3

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A cyclodextrin-modified micellar capillary electrophoretic method was developed for the chiral separation of 2-methyltaurine. The racemic mixture was separated after derivatization with dansyl chloride. The enantiomeric separation of the dansyl derivative was done using electrolyte solutions containing beta-cyclodextrin (beta-CD) or different ratios of beta- and gamma-CD. The mixture of beta- and gamma-CD optimally resolved the compound studied.

引用

页码：83 / 86

页数：4

共 9 条

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BALCHUNAS AT, 1987, ANAL CHEM, V59, P1470

[2]

BARALDI M, 1994, P 27 C NAZ FARM TOR, P36

[3] PHYSIOLOGICAL ACTIONS OF TAURINE [J].