Expression pattern of macrophage migration inhibitory factor during embryogenesis

被引:31
作者
Kobayashi, S
Satomura, K
Levsky, JM
Sreenath, T
Wistow, GJ
Semba, I
Shum, L
Slavkin, HC
Kulkarni, AB [1 ]
机构
[1] Funct Genom Unit, Bethesda, MD 20892 USA
[2] Gene Targeting Facil, Bethesda, MD 20892 USA
[3] Natl Inst Dent & Craniofacial Res, Craniofacial & Skeletal Dis Branch, Rockville, MD 20852 USA
[4] NEI, Sect Mol Struct & Funct, Bethesda, MD 20892 USA
[5] NIAMSD, Craniofacial Dev Sect, NIH, Bethesda, MD 20892 USA
关键词
macrophage migration inhibitory factor; cytokine; embryogenesis;
D O I
10.1016/S0925-4773(99)00057-X
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Although macrophage migration inhibitory factor (MIF) was originally identified as a lymphokine that inhibits the migration of macrophages, its ubiquitous expression suggests it may have a role beyond the immune system. Here we report a detailed characterization of MIF expression during mouse embryogenesis. The MIF expression pattern was found to parallel tissues specification and organogenesis. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码:153 / 156
页数:4
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