A modular approach to ligands for asymmetric pi-allyl palladium catalysed additions

被引：39

作者：

Gilbertson, SR

Chang, CWT

机构：

[1] Department of Chemistry, Washington University, St. Louis

来源：

CHEMICAL COMMUNICATIONS | 1997年 / 10期

关键词：

D O I：

10.1039/a607200c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A route to phosphinodihydrooxazoles is reported, which is used to synthesize ten new ligands whose ability to asymmetrically catalyse the addition of dimethyl malonate to 1,3-diphenylprop-2-enyl acetate is investigated; the best gave a palladium complex which catalyses the addition of dimethyl malonate to 1,3-diphenylprop-2-enyl acetate in 99% yield and 97% ee.

引用

页码：975 / 976

页数：2

共 15 条

[11] PHOSPHINOARYLOXAZOLINES AND PHOSPHINOALKYLOXAZOLINES AS NEW CHIRAL LIGANDS FOR ENANTIOSELECTIVE CATALYSIS - VERY HIGH ENANTIOSELECTIVITY IN PALLADIUM CATALYZED ALLYLIC SUBSTITUTIONS [J].