Deep Transcranial Magnetic Stimulation for treatment-resistant bipolar depression: A case report of acute and maintenance efficacy

被引：31

作者：

Bersani, Francesco Saverio ^{[1
]}

Girardi, Nicoletta ^{[1
]}

Sanna, Livia ^{[2
]}

Mazzarini, Lorenzo ^{[2
,3
]}

Santucci, Chiara ^{[2
]}

Kotzalidis, Giorgio D. ^{[2
]}

Sani, Gabriele ^{[2
]}

De Rossi, Pietro ^{[2
,6
]}

Raccah, Ruggero N. ^{[4
]}

Caltagirone, Saverio Simone ^{[2
]}

Battipaglia, Mariella ^{[2
]}

Capezzuto, Silvia ^{[3
]}

Bersani, Giuseppe ^{[5
]}

Girardi, Paolo ^{[2
,3
]}

机构：

[1] Univ Roma La Sapienza, Dept Neurol & Psychiat, I-00185 Rome, Italy

[2] Univ Roma La Sapienza, NESMOS Dept Neurosci Mental Hlth & Sensory Organs, Sch Med & Psychol, St Andrea Hosp, I-00185 Rome, Italy

[3] Suore Hosp Sacred Heart Jesus, Dept Neuropsychiat, Viterbo, Italy

[4] ATID Ltd Adv Technol Innovat Distribut, Rome, Italy

[5] Sapienza Univ Rome, Dept Med Surg Sci & Biotechnol, Latina, Italy

[6] NIMH, Bethesda, MD 20892 USA

来源：

NEUROCASE | 2013年 / 19卷 / 05期

关键词：

Deep Transcranial Magnetic Stimulation; Treatment-resistant bipolar disorder; Bipolar depression; Prefrontal cortex; Maintenance treatment of bipolar disorder; BRAIN-REGIONS; RATING-SCALE; H-COIL; ADD-ON; DISORDER; FEASIBILITY; ECT; DEFINITION; IMPAIRMENT; SYMPTOMS;

D O I：

10.1080/13554794.2012.690429

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Deep Transcranial Magnetic Stimulation (dTMS) is currently being evaluated as a possible treatment for several neuropsychiatric disorders and has been demonstrated as a safe and effective procedure. This case presents a patient with bipolar depression that has been treated with 20 daily consecutive dTMS sessions and with one dTMS session every 2 weeks for the following 3 months. Depressive symptoms improved rapidly and response was maintained during the next 6 months; cognitive performances also improved. This report suggests that add-on dTMS may help overcoming drug-resistance in bipolar depression and protect from subsequent bipolar episodes of any polarity.

引用

页码：451 / 457

页数：7

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