Initial Heroin Use Patterns Predict 5-Year Relapse: Results from a Longitudinal Cohort Study in Shanghai, China

被引：0

作者：

Li, Ruihua ^{[1
]}

Chen, Tianzhen ^{[1
]}

Jiang, Haifeng ^{[1
,2
]}

Zhong, Na ^{[1
]}

Du, Jiang ^{[1
]}

Li, Zhibin ^{[3
]}

Zhao, Yan ^{[1
]}

Sun, Haiming ^{[1
]}

Chen, Zhikang ^{[1
]}

Li, Chuanwei ^{[4
]}

Zhao, Min ^{[1
,2
,5
,6
]}

机构：

[1] Shanghai Jiao Tong Univ, Shanghai Mental Hlth Ctr, Sch Med, 600 South Wan Ping Rd, Shanghai 200030, Peoples R China

[2] Shanghai Key Lab Psychot Disorders, Shanghai, Peoples R China

[3] Jiading Mental Hlth Ctr, Shanghai, Peoples R China

[4] Soochow Univ, Suzhou Guangji Hosp, Affiliated Guangji Hosp, Suzhou, Jiangsu, Peoples R China

[5] Shanghai Jiao Tong Univ, Inst Psychol & Behav Sci, Shanghai, Peoples R China

[6] Chinese Acad Sci, CAS Ctr Excellence Brain Sci & Intelligence Techn, Shanghai, Peoples R China

来源：

INTERNATIONAL JOURNAL OF MENTAL HEALTH AND ADDICTION | 2022年 / 20卷 / 02期

基金：

国家重点研发计划;

关键词：

Heroin; Prospective study; Relapse; Trajectory; INJECTION-DRUG USE; OPIOID USE; IMPULSIVITY; COCAINE; PEOPLE; HIV; HCV;

D O I：

10.1007/s11469-020-00407-9

中图分类号：

B849 [应用心理学];

学科分类号：

040203 ;

摘要：

People start to use heroin in different patterns. This study identified three initial heroin use patterns in a heroin use cohort: No-factor initial pattern (with no factors of initial heroin use), Single-factor initial pattern (with 1 of 3 factors of initial heroin use), and Multiple-factor initial pattern (with 2 or 3 factors of initial heroin use). The cumulative heroin relapse rate was 53.3%, 62.4%, and 72.7% respectively for No-factor, Single-factor, and Multiple-factor initial patterns during the 5-year follow-up. The adjusted hazard ratio (AHR) was 1.401 (95% CI: 1.091-1.799,p = 0.008) in Single-factor initial pattern and 2.381 (95% CI: 1.546-3.668,p < 0.001) in Multiple-factor initial pattern compared to No-factor initial pattern. This study added new evidence to the impact of initial heroin use on long-term relapse risk, which suggested that initial heroin use patterns should not be neglected.

引用

页码：819 / 830

页数：12

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