A series of severe neurologic complications after bariatric surgery in France: the NEUROBAR Study

被引:12
|
作者
Alligier, Maud [1 ]
Borel, Anne-Laure [2 ]
Savey, Veronique [3 ]
Rives-Lange, Claire [4 ]
Brindisi, Marie-Claude [5 ]
Piguel, Xavier [6 ]
Nocca, David [7 ]
Monsaingeon-Henry, Maud [8 ]
Montastier, Emilie [9 ]
Beliard, Sophia [10 ]
Estour, Cecile Bossu [11 ]
Verkindt, Helene [12 ]
Coupaye, Muriel [13 ,14 ]
Lemoine, Amal [15 ]
Pierre, Antoine [16 ]
Laville, Martine [17 ]
Disse, Emmanuel [18 ]
Betry, Cecile [19 ]
机构
[1] Human Nutr Res Ctr, F CRIN FORCE Network, Lyon, France
[2] Grenoble Alpes Univ, Grenoble Alpes Univ Hosp, Dept Endocrinol Diabet & Nutr, Hypoxia Pathophysiol Lab,INSERM U1042, Grenoble, France
[3] CHU Caen Normandie, Serv Hepatogastroenterol Nutr & Chirurg Digest, Ctr Specialise Obesite, Caen, France
[4] Hop Europeen Georges Pompidou, AP HP, Dept Nutr, Paris, France
[5] CHU Dijon Bourgogne, Serv Endocrinol Diabitol Malad Metabol, CSO Bourgogne, Dijon, France
[6] CHU Poitiers, Serv Endocrinol, Nutr, Diabetol, Poitiers, France
[7] Univ Montpellier, Equipe Chirurg Bariatr, CHU Montpellier, Inst Genom Fonct,UMR 5203,CNRS,U1191 INSERM, Montpellier, France
[8] CHU Bordeaux, Hop Haut Liveque, Ctr Specialise Obesite, Serv Endocrinol Diabitol & Nutr, Pessac, France
[9] CHU Toulouse, Ctr Integre Obesite Toulouse, Serv Endocrinol Malad Metab & Nutr, Toulouse, France
[10] Aix Marseille Univ, AP HM, Nutr Metab Dis & Endocrinol Dept, INSERM,INRAE,C2 VN, Marseille, France
[11] Ctr Hosp Metropole Savoie, Chambery, France
[12] CHU Lille, Dept Gen & Endocrine Surg, Lille, France
[13] Hop Louis Mourier, AP HP, Serv Explorat Fonct, Ctr Integre Nord Francilien Prise Charge Obesite, Colombes, France
[14] Univ Paris, Inserm, UMR 1149, Colombes, France
[15] CHR Vienne, Vienne, France
[16] CHU Reims, CSO Champagne Ardenne, Hop Robert Debre, Reims, France
[17] Univ Claude Bernard Lyon 1, Hosp Civils Lyon, Ctr Integre Obesite Lyon, F CRIN FORCE Network, Pierre Benite, France
[18] Univ Claude Bernard Lyon 1, Hosp Civils Lyon, Ctr Integre Obesite Lyon, Pierre Benite, France
[19] CHU Grenoble Alpes, Serv Endocrinol, Nutr, Diabetol, Grenoble, France
关键词
Bariatric surgery; Nutritional status; Wernicke encephalopathy; Thiamine deficiency; Vitamin B deficiency; GASTRIC BYPASS;
D O I
10.1016/j.soard.2020.05.031
中图分类号
R61 [外科手术学];
学科分类号
摘要
Background: Neurologic complications after bariatric surgery are rare, but can have dramatic consequences. Little data are available on this topic. Objectives: The aim of the Neurologic complications after BARiatric surgery (NEUROBAR) study was to define, which factors (anthropometric, nutritional, surgical, etc.) were frequently associated with neurologic complications after bariatric surgery. Settings: Data were collected by the French Centers of Obesity Care Management hosted in University Hospitals. Methods: An online standardized questionnaire was designed and submitted to the 37 French Centers of Obesity Management. This questionnaire included items about patient characteristics, bariatric surgery, neurologic complications, nutritional status, and management. Patients were retrospectively included from January 2010 to November 2018. Results: Thirteen centers included 38 patients (34 females and 4 males) with neurologic complications after bariatric surgery. The 2 main bariatric procedures were gastric bypass and sleeve gastrectomy. More than half of the patients with neurologic complications had a surgical complication after bariatric surgery (53%) and gastrointestinal symptoms, including vomiting (53%). Vitamin B deficiencies were frequent (74%) including at least 47% of cases with deficiency in Vitamin B1. Conclusion: Early identification of patients with surgical complications and gastrointestinal symptoms after bariatric surgery could help prevent neurologic complications related to nutritional deficiencies. (C) 2020 American Society for Bariatric Surgery. Published by Elsevier Inc. All rights reserved.
引用
收藏
页码:1429 / 1435
页数:7
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