Integrated antimicrobial and shape memory zwitterionic copolymers

被引：6

作者：

Chen, Shaojun ^{[1
,2
,3
]}

Mei, Zhankui ^{[1
,2
,3
]}

Ren, Huanhuan ^{[1
,2
,3
]}

Zhuo, Haitao ^{[4
]}

机构：

[1] Guangdong Res Ctr Interfacial Engn Funct Mat, Shenzhen 518060, Peoples R China

[2] Shenzhen Univ, Coll Mat Sci & Engn, Shenzhen Key Lab Polymer Sci & Technol, Shenzhen 518060, Peoples R China

[3] Nanshan Dist Key Lab Biopolymers & Safety Evaluat, Shenzhen, Peoples R China

[4] Shenzhen Univ, Coll Chem & Chem Engn, Shenzhen 518060, Peoples R China

来源：

MATERIALS LETTERS | 2017年 / 189卷

关键词：

Shape memory materials; Biomaterials; Antimicrobial activity; Zwitterionic polymers; POLYMERS;

D O I：

10.1016/j.matlet.2016.11.019

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

This paper reports novel antimicrobial properties and shape memory properties of zwitterionic copolymers synthesized with 3-dimethyl(methacyloyloxyethyl) ammonium propane sulfonate (DMAPS) and acrylic acid (AA). The results demonstrate that the DMAPS-co-AA copolymer successfully integrates the antimicrobial properties and shape memory properties. The zwitterionic copolymer has good antimicrobial activity with bacteriostasis mechanism. Though the minimal inhibition concentration (MIC) of DMAPS-co-AA copolymer is much higher, zwitterionic copolymer is a good candidate of environmental friendly antimicrobial agent due to its nontoxic and biocompatibility. The shape memory properties of zwitterionic copolymer further encourage them many smart biomedical applications, such as suture and drug release.

引用

页码：74 / 77

页数：4

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