Zinc Toxicity among Galvanization Workers in the Iron and Steel Industry

被引:16
作者
El Safty, Amal [1 ]
El Mahgoub, Khalid [1 ]
Helal, Sawsan [1 ]
Maksoud, Neveen Abdel [1 ]
机构
[1] Fac Med Cairo Univ, Dept Occupat Med, Cairo, Egypt
来源
ENVIRONMENTAL CHALLENGES IN THE PACIFIC BASIN | 2008年 / 1140卷
关键词
galvanization; zinc toxicity; heavy-metal interaction; zinc fume fever;
D O I
10.1196/annals.1454.007
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Galvanization is the process of coating steel or cast iron pieces with zinc, allowing complete protection against corrosion. The ultimate goal of this work was to assess the effect of occupational exposure to zinc in the galvanization process on different metals in the human body and to detect the association between zinc exposure and its effect on the respiratory system. This study was conducted in 111 subjects in one of the major companies in the iron and steel industry. There were 61 subjects (workers) who were involved in the galvanization process. Fifty adult men were chosen as a matched reference group from other departments of the company. All workers were interviewed using a special questionnaire on occupational history and chest diseases. Ventilatory functions and chest X rays were assessed in all examined workers. Also, complete blood counts were performed, and serum zinc, iron, copper, calcium, and magnesium levels were tested. This study illustrated the relation between zinc exposure in the galvanization process and high zinc levels among exposed workers, which was associated with a high prevalence rate of metal fume fever (MFF) and low blood copper and calcium levels. There was no statistically significant difference between the exposed and control groups with regards to the magnesium level. No long-term effect of metals exposure was detected on ventilatory functions or chest X rays among the exposed workers.
引用
收藏
页码:256 / 262
页数:7
相关论文
共 21 条
[1]  
Agency for Toxic Substances and Disease Registry (ATSDR), 2005, TOX PROF ZINC UPD
[2]  
ATSDR, 2005, OX PROF ZINC
[3]   ZINC FUME FEVER [J].
BROWN, JJL .
BRITISH JOURNAL OF RADIOLOGY, 1988, 61 (724) :327-329
[4]  
DOIG A. T., 1964, ANN OCCUP HYG, V7, P223
[5]   PULMONARY EFFECTS OF INHALED ZINC-OXIDE IN HUMAN-SUBJECTS, GUINEA-PIGS, RATS, AND RABBITS [J].
GORDON, T ;
CHEN, LC ;
FINE, JM ;
SCHLESINGER, RB ;
SU, WY ;
KIMMEL, TA ;
AMDUR, MO .
AMERICAN INDUSTRIAL HYGIENE ASSOCIATION JOURNAL, 1992, 53 (08) :503-509
[6]  
Jayawardana Pushpa L., 2004, Ceylon Medical Journal, V49, P122
[7]  
Leenstra T, 2006, AM J CLIN NUTR, V83, P371
[8]  
MALO JL, 1990, EUR RESPIR J, V3, P111
[9]   The metallurgy of zinc-coated steel [J].
Marder, AR .
PROGRESS IN MATERIALS SCIENCE, 2000, 45 (03) :191-271
[10]   Short-term ventilatory effects in workers exposed to fumes containing zinc oxide: Comparison of forced oscillation technique with spirometry [J].
Pasker, HG ;
Peeters, M ;
Genet, P ;
Clement, J ;
Nemery, B ;
VandeWoestijne, KP .
EUROPEAN RESPIRATORY JOURNAL, 1997, 10 (07) :1523-1529