Clinical metric for differentiating intracranial hemangiopericytomas from meningiomas using diffusion weighted MRI

被引:9
作者
El-Ali, Alexander M. [1 ]
Agarwal, Vikas [1 ]
Thomas, Andrew [2 ]
Hamilton, Ronald L. [3 ]
Filippi, Christopher G. [4 ]
机构
[1] Univ Pittsburgh, Dept Radiol, Med Ctr, 200 Lothrop St,Suite 200 East Wing, Pittsburgh, PA 15213 USA
[2] Riverside Radiol & Intervent Associates Inc, 3525 Olentangy River R,Suite 5362, Columbus, OH 43214 USA
[3] Univ Pittsburgh, Med Ctr, Dept Pathol, Div Neuropathol, 3550 Terrace St,S724-1 Scaife Hall, Pittsburgh, PA 15261 USA
[4] Lenox Hill Hosp, Dept Radiol, Hofstra Northwell, Donald & Barbara Zucker Sch Med, 100 East 77th St, New York, NY 10075 USA
关键词
MRI; Brain tumor; Intracranial hemangiopericytoma; Meningioma; Diffusion weighted imaging;
D O I
10.1016/j.clinimag.2018.10.018
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Purpose: Intracranial Hemangiopericytomas (IHP) are dural based tumors that frequently recur/metastasize. Unfortunately, their imaging appearance overlaps significantly with more benign meningiomas. We evaluated the use of diffusion weighted imaging (DWI) to differentiate IHP from meningioma. Methods: We compared MRI of IHP tumors (WHO Grades II/III) (n = 20) to meningioma (n = 48, WHO Grade I/ II). Findings: ADC values differed between IHP (1.05 x 10-3 mm2/s) and meningiomas (0.89 x 10-3 mm2/s) (p = 0.05). Normalized ADC ratios (nADC), differed between IHP and meningiomas (1.30 vs 1.07, p = 0.03). Conclusion: Importantly, a nADC cutoff of > 1.3 was specific (96%) but not sensitive (35%) for identifying IHP.
引用
收藏
页码:1 / 5
页数:5
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