The effect of mad honey on testosterone levels of male rats

被引:5
作者
Tatli, O. [1 ]
Karaca, Y. [1 ]
Turkmen, S. [2 ]
Gulgen, G. S. [3 ]
Sahin, A. [1 ]
Eryigit, U. [1 ]
Fazli, O. [4 ]
Karaguzel, E. [5 ]
Mentese, A. [6 ]
Orem, A. [6 ]
Cansu, A. [7 ]
Turedi, S. [1 ]
Gunduz, A. [1 ]
机构
[1] Karadeniz Tech Univ, Dept Emergency Med, Fac Med, TR-61000 Trabzon, Turkey
[2] AcibademTaksim Hosp, Dept Emergency Med, Istanbul, Turkey
[3] Celal Bayar Univ, Sch VocationalHlth Serv, Dept Histol & Embryol, Manisa, Turkey
[4] Trabzon Fatih State Hosp, Dept Emergency Med, Trabzon, Turkey
[5] Karadeniz Tech Univ, Dept Urol, Fac Med, Trabzon, Turkey
[6] Karadeniz Tech Univ, Dept Biochem, Fac Med, Trabzon, Turkey
[7] Karadeniz Tech Univ, Dept Pediat Neurol, Fac Med, Trabzon, Turkey
来源
BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY | 2016年 / 117卷 / 11期
关键词
mad honey; grayanotoxin; traditional medicine; sexual performance; testosterone; RHODODENDRON; GRAYANOTOXIN;
D O I
10.4149/BLL_2016_130
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
OBJECTIVE: We aimed to investigate the effect of mad honey on sexual performance. BACKGROUND: In traditional medicine in Turkey, mad honey is used to improve appetite, to heighten mental alertness, to reduce joint pain, to eliminate gastrointestinal system pains and to increase sexual performance. METHODS: In this experimental animal study eighteen Sprague Dawley male rats were randomized into three groups, a control group, a normal honey group and a mad honey group. Rats in the treatment groups were given a daily dose of 80 mg/kg normal honey or mad honey throughout the 30-day study period. Total testosterone, free testosterone, FSH, LH, estradiol, and progesterone levels were subsequently investigated from blood sera on day 30. RESULTS: Comparison of blood total testosterone levels among the groups revealed significantly higher levels in the mad honey group compared to the normal honey and control groups (p = 0.006, p = 0.00). Free testosterone levels were also significantly higher in the mad honey group than in the normal honey and control groups (p = 0.023, p = 0.01). No statistically significant differences were determined for other hormonal measurements. CONCLUSIONS: This study revealed a significant increase in both total and free testosterone levels in mad-honey group (Tab. 1, Fig. 2, Ref. 16). Text in PDF www.elis.sk.
引用
收藏
页码:677 / 680
页数:4
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