Fabrication Strategies Towards Hydrogels for Biomedical Application: Chemical and Mechanical Insights

被引:17
作者
Acciaretti, Federico [1 ]
Vesentini, Simone [2 ]
Cipolla, Laura [1 ]
机构
[1] Univ Milano Bicocca, Dept Biotechnol & Biosci, Piazza Sci 2, I-20126 Milan, Italy
[2] Politecn Milano Italy, Dept Elect Informat & Bioengn, Piazza Leonardo da Vinci 32, I-20133 Milan, Italy
关键词
hydrogels; cross-linking; dynamic reactions; smart hydrogels; stimuli responsiveness; COLLAGEN CROSS-LINKING; RESPONSIVE HYDROGELS; EXTRACELLULAR-MATRIX; POLYMERIC HYDROGELS; DRUG-DELIVERY; GENIPIN; CULTURE; CELLS; PEG; BIOMATERIAL;
D O I
10.1002/asia.202200797
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
This review aims at giving selected chemical and mechanical insights on design criteria that should be taken into account in hydrogel production for biomedical applications. Particular emphasis will be given to the chemical aspects involved in hydrogel design: macromer chemical composition, cross-linking strategies and chemistry towards "conventional" and smart/stimuli responsive hydrogels. Mechanical properties of hydrogels in view of regenerative medicine applications will also be considered.
引用
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页数:22
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