Multidrug resistant Mycobacterium leprae from patients with leprosy

被引：122
作者：
Maeda, S
Matsuoka, M
Nakata, N
Kai, M
Maeda, Y
Hashimoto, K
Kimura, H
Kobayashi, K
Kashiwabara, Y
机构：
[1] Natl Inst Infect Dis, Leprosy Res Ctr, Tokyo 1890002, Japan
[2] Osaka City Univ, Grad Sch Med, Dept Host Def, Abeno Ku, Osaka 5458585, Japan
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2001年 / 45卷 / 12期
关键词：
D O I：
10.1128/AAC.45.12.3635-3639.2001
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Sequences of the folP1, rpoB, and gyrA genes were analyzed for 88 isolates of Mycobacterium leprae from leprosy patients in Japan, Haiti, Indonesia, Pakistan, and the Philippines. Thirteen isolates (14.8%) showed representative mutations in more than two genes, suggesting the emergence of multidrug-resistant M. leprae.
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页码：3635 / 3639
页数：5
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