Pd/C-catalyzed chemoselective hydrogenation in the presence of diphenylsulfide

被引：135

作者：

Mori, Akinori ^{[1
]}

Miyakawa, Yumi ^{[1
]}

Ohashi, Eri ^{[1
]}

Haga, Tomoko ^{[1
]}

Maegawa, Tomohiro ^{[1
]}

Sajiki, Hironao ^{[1
]}

机构：

[1] Gifu Pharmaceut Univ, Med Chem Lab, Gifu 5028585, Japan

来源：

ORGANIC LETTERS | 2006年 / 8卷 / 15期

关键词：

D O I：

10.1021/ol061147j

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A Pd/C-catalyzed chemoselective hydrogenation using diphenylsulfide as a catalyst poison has been developed. This methodology selectively hydrogenates olefin and acetylene functionalities without hydrogenolysis of aromatic carbonyls and halogens, benzyl esters, and N-Cbz protective groups.

引用

页码：3279 / 3281

页数：3

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