Incidence and Main Risk Factors for Severe Retinopathy of Prematurity in Infants Weighing Less Than 1000 Grams in Brazil

被引:11
作者
Fortes Filho, Joao Borges [1 ]
Borges Fortes, Barbara Gastal [1 ]
Tartarella, Marcia Beatriz [2 ]
Procianoy, Renato Soibelmann [3 ]
机构
[1] Univ Fed Rio Grande do Sul, Hosp Clin Porto Alegre, Sch Med, Dept Ophthalmol, BR-90035903 Porto Alegre, RS, Brazil
[2] Univ Fed Sao Paulo, Sch Med, Dept Ophthalmol, BR-04023062 Sao Paulo, Brazil
[3] Univ Fed Rio Grande do Sul, Hosp Clin Porto Alegre, Sch Med, Dept Pediat,Newborn Sect, BR-90035903 Porto Alegre, RS, Brazil
关键词
prematurity; retinopathy of prematurity; incidence; risk factors; blindness; prevention; 27 WEEKS GESTATION; THRESHOLD RETINOPATHY; NATURAL-HISTORY; PRETERM INFANTS; BIRTH; BORN;
D O I
10.1093/tropej/fmt036
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Objectives: This study evaluated the incidence and risk factors for severe retinopathy of prematurity (ROP) in babies <1000 g at Porto Alegre, Brazil. Methods: Prospective cohort study including premature children with birth weight <= 1000 g was conducted. Main outcome was the occurrence of severe ROP needing treatment. Results: A total of 157 infants were included. Severe ROP occurred in 20 infants (12.7%). Nineteen patients were treated by laser photocoagulation. Main risk factors for severe ROP were gestational age (P=0.029), infant's weight measured at sixth week of life (P<0.001) and number of days of oxygen therapy under mechanical ventilation (P<0.001). After logistic regression, infant's weight at sixth week of life and number of days in mechanical ventilation were associated to severe ROP. Conclusions: We reported the incidence of 12.7% of severe ROP among babies born <= 1000 g in our institution. Laser photocoagulation was effective to stabilize the disease among 19 treated patients.
引用
收藏
页码:502 / 506
页数:5
相关论文
共 30 条
[1]   Screening for Retinopathy of Prematurity in Infants Born Before 27 Weeks' Gestation in Sweden [J].
Austeng, Dordi ;
Kallen, Karin B. M. ;
Hellstrom, Ann ;
Jakobsson, Peter G. ;
Johansson, Kent ;
Tornqvist, Kristina ;
Wallin, Agneta ;
Holmstrom, Gerd E. .
ARCHIVES OF OPHTHALMOLOGY, 2011, 129 (02) :167-172
[2]   Natural History of Retinopathy of Prematurity in Infants Born Before 27 Weeks' Gestation in Sweden [J].
Austeng, Dordi ;
Kallen, Karin B. M. ;
Hellstrom, Ann ;
Tornqvist, Kristina ;
Holmstrom, Gerd E. .
ARCHIVES OF OPHTHALMOLOGY, 2010, 128 (10) :1289-1294
[3]   Prevalence of retinopathy of prematurity in Latin America [J].
Carrion, Juliana Zimmermann ;
Fortes Filho, Joao Borges ;
Tartarella, Marcia Beatriz ;
Zin, Andrea ;
Jornada, Ignozy Dorneles, Jr. .
CLINICAL OPHTHALMOLOGY, 2011, 5 :1687-1695
[4]   Retinopathy of prematurity in extremely low birth weight infants in Malaysia [J].
Choo, May May ;
Martin, Frank Joseph ;
Theam, Lim Chin ;
U-Teng, Chan .
JOURNAL OF AAPOS, 2009, 13 (05) :446-449
[5]  
Coats DK, 2000, J AAPOS, V4, P183, DOI 10.1016/S1091-8531(00)70011-5
[6]  
Cryotherapy for Retinopathy of Prematurity Cooperative Group, 1988, PEDIATRICS, V81, P697
[7]   Inflammation and retinopathy of prematurity [J].
Dammann, Olaf .
ACTA PAEDIATRICA, 2010, 99 (07) :975-977
[8]   Immaturity, perinatal inflammation, and retinopathy of prematurity: A multi-hit hypothesis [J].
Dammann, Olaf ;
Brinkhaus, Maria-Jantje ;
Bartels, Dorothee B. ;
Doerdelmann, Michael ;
Dressier, Frank ;
Kerk, Julia ;
Doerk, Thilo ;
Darnmann, Christiane E. L. .
EARLY HUMAN DEVELOPMENT, 2009, 85 (05) :325-329
[9]   Screening Examination of Premature Infants for Retinopathy of Prematurity [J].
Fierson, Walter M. ;
Saunders, Richard A. ;
Good, William ;
Palmer, Earl A. ;
Phelps, Dale ;
Reynolds, James ;
Chiang, Michael F. ;
Ruben, James B. ;
Granet, David B. ;
Blocker, Richard J. ;
Bradford, Geoffrey E. ;
Karr, Daniel J. ;
Lueder, Gregg T. ;
Lehman, Sharon S. ;
Siatkowski, R. Michael .
PEDIATRICS, 2013, 131 (01) :189-195
[10]   The influence of gestational age on the dynamic behavior of other risk factors associated with retinopathy of prematurity (ROP) [J].
Fortes Filho, Joao Borges ;
Eckert, Gabriela Unchalo ;
Valiatti, Fabiana Borba ;
Batista dos Santos, Paula Gabriela ;
da Costa, Marlene Coelho ;
Procianoy, Renato Soibelmann .
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 2010, 248 (06) :893-900