Chemistry of Iminofurans. Recyclization of Ethyl 2-[2-Oxo-5-phenylfuran-3(2H)-ylideneamino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate in Reaction with Amines

被引：21

作者：

Shipilovskikh, S. A. ^{[1
]}

Shipilovskikh, D. A. ^{[1
]}

Rubtsov, A. E. ^{[1
]}

机构：

[1] Perm State Univ, Ul Bukireva 15, Perm 614990, Russia

来源：

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2017年 / 53卷 / 01期

基金：

俄罗斯基础研究基金会;

关键词：

ANALGESIC ACTIVITY; INTRAMOLECULAR CYCLIZATION; ACIDS; DECYCLIZATION; DERIVATIVES; SALTS;

D O I：

10.1134/S1070428017010274

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of ethyl 2-[2-oxo-5-phenylfuran-3(2H)-ylideneamino]-4,5,6,7-tetrahydro-1-benzothiophene- 3-carboxylate with primary amines (RNH2) in toluene under reflux led to the formation of the corresponding ethyl 2-[(1-R-5-hydroxy-2-oxo-5-phenyl-2,5-dihydro-1H-pyrrol-3-yl) amino]-4,5,6,7-tetrahydro-1- benzothiophene-3-carboxylates. The product structure was determined by X-ray analysis.

引用

页码：137 / 140

页数：4

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