A Click Reaction for Fluorescent Labelling: Application of the 1,3-Dipolar Cycloaddition Reaction

被引:18
|
作者
Langhals, Heinz [1 ]
Obermeier, Andreas [1 ]
机构
[1] Univ Munich, LMU, Dept Chem, D-81377 Munich, Germany
关键词
Dyes; Fluorescence spectroscopy; Hormones; Photochemistry; Receptors;
D O I
10.1002/ejoc.200800805
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The copper-catalysed 1,3-dipolar cycloaddition of azides with terminal alkynes was use to introduce a highly fluorescent and photostable perylene-tetracarboxdiimide label. Fluorescent labelling of human hormones and applications are discussed. ((C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)
引用
收藏
页码:6144 / 6151
页数:8
相关论文
共 50 条
  • [21] 1,3-DIPOLAR CYCLOADDITION REACTION OF SUBSTITUTED TRIMETHYLSTANNYLACETYLENES WITH NITRILE OXIDES
    SAKAMOTO, T
    UCHIYAMA, D
    KONDO, Y
    YAMANAKA, H
    CHEMICAL & PHARMACEUTICAL BULLETIN, 1993, 41 (03) : 478 - 480
  • [22] A computational study of the 1,3-dipolar cycloaddition reaction mechanism for nitrilimines
    Mawhinney, RC
    Muchall, HM
    Peslherbe, GH
    CANADIAN JOURNAL OF CHEMISTRY, 2005, 83 (09) : 1615 - 1625
  • [23] PHOTO-INDUCED 1,3-DIPOLAR CYCLOADDITION REACTION OF AZIRIDINEDICARBOXIMIDE
    OIDA, S
    OHKI, E
    CHEMICAL & PHARMACEUTICAL BULLETIN, 1969, 17 (12) : 2461 - +
  • [24] Synthesis and Characterization of Isoxazolidine Derivatives by 1,3-Dipolar Cycloaddition Reaction
    Al-Ghorbani, Mohammad
    Al-Timari, Usama S.
    Fadh, Taha A.
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2019, 29 (02) : 131 - 137
  • [25] CATALYTIC EFFECT OF GALLIUM CHLORIDE IN THE 1,3-DIPOLAR CYCLOADDITION REACTION
    KISELEV, VD
    KHUZYASHEVA, DG
    KONOVALOV, AI
    ZHURNAL ORGANICHESKOI KHIMII, 1983, 19 (04): : 884 - 885
  • [26] 1,3-Dipolar cycloaddition reaction of [60]fullerene with thiocarbonyl ylide and synthetic application of the cycloadduct
    Ishida, H
    Itoh, K
    Ohno, M
    TETRAHEDRON, 2001, 57 (09) : 1737 - 1747
  • [27] 1,3-Dipolar cycloaddition reaction on carbohydrate template: Stereoselective synthesis of glycospiroheterocycles
    Prasanna, R.
    Purushothaman, S.
    Raghunathan, R.
    TETRAHEDRON, 2020, 76 (35)
  • [28] Gold nanoparticle as a Lewis acid catalyst in 1,3-dipolar cycloaddition reaction
    Yazdani, Hossein
    Pardis, Samira
    Loni, Masood
    Bazgir, Ayoob
    CATALYSIS COMMUNICATIONS, 2020, 134
  • [29] Computational study of the energetics governing the regiochemistry of a 1,3-dipolar cycloaddition reaction
    Esempio, Phillip L.
    Trujillo, Hernando A.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2014, 247
  • [30] Aldimines of 5-aminouracil as reagents in 1,3-dipolar cycloaddition reaction
    Dominika Jakubiec
    Krzysztof Z. Walczak
    Monatshefte für Chemie - Chemical Monthly, 2011, 142 : 1155 - 1161