Primary cutaneous lymphoblastic lymphoma presenting in an 8-week old infant

被引：21

作者：

Trupiano, JK

Bringelsen, K

Hsi, ED

机构：

[1] Cleveland Clin Fdn, Sect Hematopathol, Cleveland, OH 44195 USA

[2] Cleveland Clin Fdn, Dept Pathol, Cleveland, OH 44195 USA

[3] Cleveland Clin Fdn, Dept Pediat Hematol Oncol, Cleveland, OH 44195 USA

来源：

JOURNAL OF CUTANEOUS PATHOLOGY | 2002年 / 29卷 / 02期

关键词：

D O I：

10.1034/j.1600-0560.2001.290208.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Background: We report a case of primary cutaneous lymphoblastic lymphoma (LBL) presenting in an 8-week-old infant. Methods: Histopathology and flow cytometric analysis confirmed the diagnosis of a lymphoblastic lymphoma. The cells expressed CD 19, CD20, CD34 and surface inurumoglobulin (sIg). Results: The cells were negative for TdT and CD99. This unusual immunophenotype has been described as "transitional pre-B-cell", in that the cells express both immature markers (CD34) and mature markers (sIg). Conclusions: To our knowledge, only five other cases of sIg positive precursor B-cell LBL have been reported in the literature. This may represent the youngest reported case of primary cutaneous LBL, occurring at 8 weeks of age.

引用

页码：107 / 112

页数：6

共 32 条

[21] Precursor B-lymphoblastic lymphoma presenting as a solitary bone tumor and mimicking Ewing's sarcoma - A report of four cases and review of the literature [J].