The Dynamics of an HTLV-1 System with Cell-Mediated Immune Response

被引：0
|
作者：
Li, Sumei [1 ]
Jia, Jiteng [2 ]
机构：
[1] Xian Univ Sci & Technol, Sch Sci, Xian 710054, Shaanxi, Peoples R China
[2] Xidian Univ, Sch Math & Stat, Xian 710071, Shaanxi, Peoples R China
来源：
2018 5TH INTERNATIONAL CONFERENCE ON SYSTEMS AND INFORMATICS (ICSAI) | 2018年
基金：
中国国家自然科学基金;
关键词：
HTLV-1; Global stability; Tax expression; Immune response; BACKWARD BIFURCATION; I INFECTION; VIRUS; HISTORY; MODEL;
D O I：
暂无
中图分类号：
TM [电工技术]; TN [电子技术、通信技术];
学科分类号：
0808 ; 0809 ;
摘要：
In this paper, we formulated a four dimensional system to explore the interaction between Tax-expression and CTL immune response in HTLV-1 infected individuals. Two parameters (R-0 and R-1) are derived to study the system dynamics. We analyzed the existence and stability of the disease-free equilibrium, the immune-free equilibrium and the infected equilibrium theoretically. By numerical simulations, the impact of Tax-expression and immune response on the proviral load were demonstrated.
引用
收藏
页码：638 / 643
页数：6
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