The Dynamics of an HTLV-1 System with Cell-Mediated Immune Response

被引：0
|
作者：
Li, Sumei [1 ]
Jia, Jiteng [2 ]
机构：
[1] Xian Univ Sci & Technol, Sch Sci, Xian 710054, Shaanxi, Peoples R China
[2] Xidian Univ, Sch Math & Stat, Xian 710071, Shaanxi, Peoples R China
来源：
2018 5TH INTERNATIONAL CONFERENCE ON SYSTEMS AND INFORMATICS (ICSAI) | 2018年
基金：
中国国家自然科学基金;
关键词：
HTLV-1; Global stability; Tax expression; Immune response; BACKWARD BIFURCATION; I INFECTION; VIRUS; HISTORY; MODEL;
D O I：
暂无
中图分类号：
TM [电工技术]; TN [电子技术、通信技术];
学科分类号：
0808 ; 0809 ;
摘要：
In this paper, we formulated a four dimensional system to explore the interaction between Tax-expression and CTL immune response in HTLV-1 infected individuals. Two parameters (R-0 and R-1) are derived to study the system dynamics. We analyzed the existence and stability of the disease-free equilibrium, the immune-free equilibrium and the infected equilibrium theoretically. By numerical simulations, the impact of Tax-expression and immune response on the proviral load were demonstrated.
引用
收藏
页码：638 / 643
页数：6
相关论文
共 50 条
  • [1] Cellular immune response to HTLV-1
    Bangham, CRM
    Osame, M
    ONCOGENE, 2005, 24 (39) : 6035 - 6046
  • [2] Cellular immune response to HTLV-1
    Charles R M Bangham
    Mitsuhiro Osame
    Oncogene, 2005, 24 : 6035 - 6046
  • [3] HTLV-1, Immune Response and Autoimmunity
    Quaresma, Juarez A. S.
    Yoshikawa, Gilberto T.
    Koyama, Roberta V. L.
    Dias, George A. S.
    Fujihara, Satomi
    Fuzii, Hellen T.
    VIRUSES-BASEL, 2016, 8 (01):
  • [4] The immune control of HTLV-1 infection: selection forces and dynamics
    Bangham, Charles R. M.
    Meekings, Kiran
    Toulza, Frederic
    Nejmeddine, Mohamed
    Majorovits, Endre
    Asquith, Becca
    Taylor, Graham P.
    FRONTIERS IN BIOSCIENCE-LANDMARK, 2009, 14 : 2889 - 2903
  • [5] Dynamics of the cell-mediated immune response to tumour growth
    Lopez, Alvaro G.
    Seoane, Jesus M.
    Sanjuan, Miguel A. F.
    PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES, 2017, 375 (2096):
  • [6] Association of Tuberculosis Status with Neurologic Disease and Immune Response in HTLV-1 Infection
    Souza, Anselmo
    Carvalho, Natlia
    Neves, Yuri
    Santos, Silvane Braga
    Bastos, Maria de Lourdes
    Arruda, Sergio
    Netto, Eduardo Martins
    Glesby, Marshall J.
    Carvalho, Edgar
    AIDS RESEARCH AND HUMAN RETROVIRUSES, 2017, 33 (11) : 1126 - 1133
  • [7] DYNAMICS OF A HIV-1 INFECTION MODEL WITH CELL-MEDIATED IMMUNE RESPONSE AND INTRACELLULAR DELAY
    Zhu, Huiyan
    Zou, Xingfu
    DISCRETE AND CONTINUOUS DYNAMICAL SYSTEMS-SERIES B, 2009, 12 (02): : 511 - 524
  • [8] Interference with immune function by HTLV-1
    Goon, PKC
    Bangham, CRM
    CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 2004, 137 (02) : 234 - 236
  • [9] Conflicting effects of poly(ADP-ribose) polymerase inhibitor on cell-mediated and virion-mediated HTLV-1 infection
    Tanaka, Masakazu
    Tanaka, Koji
    Ida, Chieri
    Oue, Atsushi
    Yamashita, Sachiko
    Yao, Jinchun
    Takenouchi, Norihiro
    Miwa, Masanao
    VIRUS RESEARCH, 2019, 270
  • [10] HTLV-1 HBZ Viral Protein: A Key Player in HTLV-1 Mediated Diseases
    Baratella, Marco
    Forlani, Greta
    Accolla, Roberto S.
    FRONTIERS IN MICROBIOLOGY, 2017, 8
12345