Synthesis of new alkoxy/sulfonate-substituted carbene precursors derived from [2.2]paracyclophane and their application in the asymmetric arylation of aldehydes

被引：29

作者：

Duan, Wenzeng ^{[1
]}

Ma, Yudao ^{[1
]}

Qu, Bo ^{[1
]}

Zhao, Lei ^{[1
]}

Chen, Jianqiang ^{[1
]}

Song, Chun ^{[1
]}

机构：

[1] Shandong Univ, Dept Chem, Jinan 250100, Peoples R China

来源：

TETRAHEDRON-ASYMMETRY | 2012年 / 23卷 / 18-19期

基金：

中国国家自然科学基金;

关键词：

N-HETEROCYCLIC CARBENES; OLEFIN METATHESIS CATALYSTS; CONJUGATE ADDITION; ARYLBORONIC ACIDS; GRIGNARD-REAGENTS; IMIDAZOLIUM SALTS; ARYL CHLORIDES; LIGANDS; COMPLEXES; DERIVATIVES;

D O I：

10.1016/j.tetasy.2012.09.001

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A series of novel planar chiral alkoxy/sulfonate-substituted carbene precursors have been designed and synthesized. They were used as N-heterocyclic carbene ligands in the Rh-catalyzed asymmetric addition of arylboronic acids to aromatic aldehydes, affording chiral diarylmethanols with high yields and moderate enantioselectivities. (C) 2012 Elsevier Ltd. All rights reserved.

引用

页码：1369 / 1375

页数：7

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