Sitagliptin and Acute Pancreatitis: Cases and Literature Review

被引：1

作者：

Kale Koroglu, Banu ^{[1
]}

Songur, Yildiran ^{[2
]}

Ersoy, Ismail Hakki ^{[1
]}

Koroglu, Mert ^{[3
]}

Akin, Mete ^{[2
]}

Tamer, M. Numan ^{[1
]}

机构：

[1] Suleyman Demirel Univ, Fac Med, Dept Endocrinol & Metab, TR-32200 Isparta, Turkey

[2] Suleyman Demirel Univ, Fac Med, Dept Gastroenterol, TR-32200 Isparta, Turkey

[3] Suleyman Demirel Univ, Fac Med, Dept Radiol, TR-32200 Isparta, Turkey

来源：

TURKIYE KLINIKLERI TIP BILIMLERI DERGISI | 2012年 / 32卷 / 03期

关键词：

Sitagliptin; incretins; drug toxicity; acute necrotizing pancreatitis; PEPTIDASE-4 INHIBITOR SITAGLIPTIN; TYPE-2; EXENATIDE; SAFETY; MONOTHERAPY; MANAGEMENT; EFFICACY; THERAPY; SYSTEM; RAT;

D O I：

10.5336/medsci.2010-20920

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Acute pancreatitis is the rapid onset inflammation of the pancreas. Medications are rare but important and rising cause of acute pancreatitis and account for approximately 2% of all cases. Sitagliptin is a potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor for the treatment of patients with type 2 diabetes mellitus and acts by increasing active incretin hormone concentrations. Adverse effects including constipation, nausea, nasopharyngitis, urinary tract infection and dizziness were reported. We reported a case with acute pancreatitis that seems to be induced by sitagliptin.

引用

页码：859 / 864

页数：6

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