Sitagliptin and Acute Pancreatitis: Cases and Literature Review

被引：1
|
作者：
Kale Koroglu, Banu [1 ]
Songur, Yildiran [2 ]
Ersoy, Ismail Hakki [1 ]
Koroglu, Mert [3 ]
Akin, Mete [2 ]
Tamer, M. Numan [1 ]
机构：
[1] Suleyman Demirel Univ, Fac Med, Dept Endocrinol & Metab, TR-32200 Isparta, Turkey
[2] Suleyman Demirel Univ, Fac Med, Dept Gastroenterol, TR-32200 Isparta, Turkey
[3] Suleyman Demirel Univ, Fac Med, Dept Radiol, TR-32200 Isparta, Turkey
来源：
TURKIYE KLINIKLERI TIP BILIMLERI DERGISI | 2012年 / 32卷 / 03期
关键词：
Sitagliptin; incretins; drug toxicity; acute necrotizing pancreatitis; PEPTIDASE-4 INHIBITOR SITAGLIPTIN; TYPE-2; EXENATIDE; SAFETY; MONOTHERAPY; MANAGEMENT; EFFICACY; THERAPY; SYSTEM; RAT;
D O I：
10.5336/medsci.2010-20920
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Acute pancreatitis is the rapid onset inflammation of the pancreas. Medications are rare but important and rising cause of acute pancreatitis and account for approximately 2% of all cases. Sitagliptin is a potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor for the treatment of patients with type 2 diabetes mellitus and acts by increasing active incretin hormone concentrations. Adverse effects including constipation, nausea, nasopharyngitis, urinary tract infection and dizziness were reported. We reported a case with acute pancreatitis that seems to be induced by sitagliptin.
引用
收藏
页码：859 / 864
页数：6
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