Bevacizumab in therapy-refractory epistaxis. Case report of low-dose antibody therapy for hereditary hemorrhagic telangiectasia

被引：2
作者：
Rohrmeier, C. [1 ]
Kuehnel, T. S. [1 ]
机构：
[1] Univ Klinikum Regensburg, Klin Hals Nasen Ohren Heilkunde Kopf & Halschirur, D-93053 Regensburg, Germany
来源：
HNO | 2012年 / 60卷 / 11期
关键词：
Hereditary hemorrhagic telangiectasia; Osler disease; Bevacizumab; Epistaxis; Case report;
D O I：
10.1007/s00106-011-2458-x
中图分类号：
R76 [耳鼻咽喉科学];
学科分类号：
100213 ;
摘要：
We report on the submucosal injection of bevacizumab (Avastin) at a dose of 0.3 to 3.75 mg per side in a patient with hereditary hemorrhagic telangiectasia. Application of such low doses has not been described in the literature yet. Our case report shows the positive effect of low-dose bevacizumab on therapy-refractory epistaxis. No complications were caused by the bevacizumab treatment.
引用
收藏
页码：1003 / 1006
页数：4
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