Bevacizumab in therapy-refractory epistaxis. Case report of low-dose antibody therapy for hereditary hemorrhagic telangiectasia

被引：2

作者：

Rohrmeier, C. ^{[1
]}

Kuehnel, T. S. ^{[1
]}

机构：

[1] Univ Klinikum Regensburg, Klin Hals Nasen Ohren Heilkunde Kopf & Halschirur, D-93053 Regensburg, Germany

来源：

HNO | 2012年 / 60卷 / 11期

关键词：

Hereditary hemorrhagic telangiectasia; Osler disease; Bevacizumab; Epistaxis; Case report;

D O I：

10.1007/s00106-011-2458-x

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

We report on the submucosal injection of bevacizumab (Avastin) at a dose of 0.3 to 3.75 mg per side in a patient with hereditary hemorrhagic telangiectasia. Application of such low doses has not been described in the literature yet. Our case report shows the positive effect of low-dose bevacizumab on therapy-refractory epistaxis. No complications were caused by the bevacizumab treatment.

引用

页码：1003 / 1006

页数：4

共 48 条

[21] Treatment with low-dose tacrolimus inhibits bleeding complications in a patient with hereditary hemorrhagic telangiectasia and pulmonary arterial hypertension [J].

Sommer, N. ;

Droege, F. ;

Gamen, K. E. ;

Geisthoff, U. ;

Gall, H. ;

Tello, K. ;

Richter, M. J. ;

Deubner, L. M. ;

Schmiedel, R. ;

Hecker, M. ;

Spiekerkoetter, E. ;

Wirsching, K. ;

Seeger, W. ;

Ghofrani, H. A. ;

Pullamsetti, S. .

PULMONARY CIRCULATION, 2018, 9 (02)

[22] Case report: Diagnosis of hereditary hemorrhagic telangiectasia (Osler Weber Rendu Syndrome) in a 23-year-old male presented with anemia and thrombocytopenia and its response to bevacizumab [J].

Yunus, Hamza ;

Amin, Said ;

Ul Haq, Furqan ;

Ali, Waqar ;

Hamid, Tanveer ;

Ali, Wajid ;

Ullah, Basharat ;

Bai, Payal .

FRONTIERS IN MEDICINE, 2022, 9

[23] Low-dose atorvastatin therapy induced rhabdomyolysis in a liver cirrhosis patient - a case report [J].

Bhattarai, Shashank ;

Pradhan, Sandip ;

Bhattarai, Shraddha .

ANNALS OF MEDICINE AND SURGERY, 2023, 85 (10) :5232-5234

[24] Middle meningeal artery embolization and tranexamic acid therapy for subdural hematoma in a patient with hereditary hemorrhagic telangiectasia: illustrative case [J].

Kushmakov, Robert ;

Cazorla-Morales, Ilona ;

Brenner, Keith ;

Araten, David ;

Shapiro, Maksim ;

Raz, Eytan ;

Placantonakis, Dimitris G. .

JOURNAL OF NEUROSURGERY-CASE LESSONS, 2024, 8 (19)

[25] Treatment of intracardiac thrombi using ultra-slow low-dose thrombolytic therapy: A case report [J].

Pinto, Ricardo Alves ;

Torres, Sofia ;

Formigo, Mariana ;

Sousa, Elsa ;

Coentrao, Luis ;

Neves, Aida ;

Macedo, Filipe ;

Maciel, Maria Julia ;

Oliveira, Teresa .

REVISTA PORTUGUESA DE CARDIOLOGIA, 2023, 42 (11) :925-928

[26] Colchicine triggered severe rhabdomyolysis after long-term low-dose simvastatin therapy: a case report [J].

Frydrychowicz C. ;

Pasieka B. ;

Pierer M. ;

Mueller W. ;

Petros S. ;

Weidhase L. .

Journal of Medical Case Reports, 11 (1) :1-5

[27] Response to case report: Airway autoimmune responses in severe eosinophilic asthma following low-dose Mepolizumab therapy [J].

Pouliquen, I. J. ;

Howarth, P. ;

Austin, D. ;

Gunn, G. ;

Meyer, E. ;

Price, R. G. ;

Bradford, E. .

ALLERGY ASTHMA AND CLINICAL IMMUNOLOGY, 2017, 13

[28] Response to case report: Airway autoimmune responses in severe eosinophilic asthma following low-dose Mepolizumab therapy [J].

I. J. Pouliquen ;

P. Howarth ;

D. Austin ;

G. Gunn ;

E. Meyer ;

R. G. Price ;

E. Bradford .

Allergy, Asthma & Clinical Immunology, 13

[29] Case Report: single low-dose of denosumab as a trigger of MRONJ development in a patient with osteoporosis after bisphosphonate therapy [J].

Szaraz, David ;

Perina, Vojtech ;

Treglerova, Jana ;

Machacek, Ctirad ;

Zendulka, Ondrej ;

Borilova Linhartova, Petra .

FRONTIERS IN ORAL HEALTH, 2024, 5

[30] Treatment with Tumor-Treating Fields Therapy and Pulse Dose Bevacizumab in Patients with Bevacizumab-Refractory Recurrent Glioblastoma: A Case Series [J].

Ansstas, George ;

Tran, David D. .

CASE REPORTS IN NEUROLOGY, 2016, 8 (01) :1-9

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