Cardiac amyloidosis: A case report and review of literature

被引：14

作者：

Taiwo, Adeyemi Adedamola ^{[1
]}

Alapati, Lavanya ^{[2
]}

Movahed, Assad ^{[2
]}

机构：

[1] East Carolina Univ, Dept Internal Med, Greenville, NC 27834 USA

[2] East Carolina Univ, East Carolina Heart Inst, Dept Cardiovasc Sci, 115 Heart Dr, Greenville, NC 27834 USA

来源：

WORLD JOURNAL OF CLINICAL CASES | 2019年 / 7卷 / 06期

关键词：

Cardiac amyloidosis; Restrictive cardiomyopathy; Transthyretin; Case report; LIGHT-CHAIN AMYLOIDOSIS; AL AMYLOIDOSIS; WILD-TYPE; MAGNETIC-RESONANCE; IMPROVED OUTCOMES; TRANSTHYRETIN; DIAGNOSIS; TRANSPLANTATION; PATHOPHYSIOLOGY; SCINTIGRAPHY;

D O I：

10.12998/wjcc.v7.i6.742

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

BACKGROUND Cardiac amyloidosis, a disease caused by the precipitation of amyloid proteins in the myocardial extracellular matrix has been historically difficult to diagnose due to lack of specific clinical manifestations and necessity of biopsy to demonstrate amyloid deposition. However, advances in cardiovascular imaging techniques have facilitated earlier recognition of this disease. In addition, while once thought of as incurable, treatment strategies are emerging for cardiac amyloidosis, making early diagnosis essential. CASE SUMMARY We outline the case of a 73 years old African American female who was admitted with sudden onset shortness of breath and found to be in cardiogenic shock. Cardiac amyloidosis was suspected due to discordance between electrocardiogram and echocardiogram findings and this was subsequently confirmed with the aid of scintigraphy and an endomyocardial biopsy. CONCLUSION Our objective is to highlight the diagnostic evaluation and clinical implications of cardiac amyloidosis.

引用

页码：742 / 752

页数：11

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