Arp2/3 and scar: Plants move to the fore

被引:63
作者
Deeks, MJ [1 ]
Hussey, PJ [1 ]
机构
[1] Univ Durham, Sch Biol & Biomed Sci, Integrat Cell Biol Lab, Durham DH1 3LE, England
基金
英国生物技术与生命科学研究理事会;
关键词
D O I
10.1038/nrm1765
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The actin-nucleating Arp2/3 complex is essential for life in yeast and animals, but not in plants, in which mutants of Arp2/3 complex components show relatively minor developmental abnormalities. Animal cells control the activity of the Arp2/3 complex through the suppressor of cyclic AMP receptor ( SCAR) complex to achieve cell motility. Amazingly, plants have also retained the SCAR cell-motility pathway, and now provide a unique model for the study of new aspects of SCAR function in the absence of cell motility.
引用
收藏
页码:954 / 964
页数:11
相关论文
共 115 条
[51]   Role of SH3 domain-containing proteins in clathrin-mediated vesicle trafficking in Arabidopsis [J].
Lam, BCH ;
Sage, TL ;
Bianchi, F ;
Blumwald, E .
PLANT CELL, 2001, 13 (11) :2499-2512
[52]   Requirements for Arabidopsis ATARP2 and ATARP3 during epidermal development [J].
Le, J ;
El-Assal, SED ;
Basu, D ;
Saad, ME ;
Szymanski, DB .
CURRENT BIOLOGY, 2003, 13 (15) :1341-1347
[53]   Fission yeast myosin-I, Myo1p, stimulates actin assembly by Arp2/3 complex and shares functions with WASp [J].
Lee, WL ;
Bezanilla, M ;
Pollard, TD .
JOURNAL OF CELL BIOLOGY, 2000, 151 (04) :789-799
[54]   The putative Arabidopsis Arp2/3 complex controls leaf cell morphogenesis [J].
Li, SD ;
Blanchoin, L ;
Yang, ZB ;
Lord, EM .
PLANT PHYSIOLOGY, 2003, 132 (04) :2034-2044
[55]   Arabidopsis NAP and PIR regulate actin-based cell morphogenesis and multiple developmental processes [J].
Li, YH ;
Sorefan, K ;
Hemmann, G ;
Bevan, MW .
PLANT PHYSIOLOGY, 2004, 136 (03) :3616-3627
[56]   Evidence for physical and functional interactions among two Saccharomyces cerevisiae SH3 domain proteins, an adenylyl cyclase-associated protein and the actin cytoskeleton [J].
Lila, T ;
Drubin, DG .
MOLECULAR BIOLOGY OF THE CELL, 1997, 8 (02) :367-385
[57]   Imaging sites of N-WASP activity in lamellipodia and invadopodia of carcinoma cells [J].
Lorenz, M ;
Yamaguchi, H ;
Wang, YR ;
Singer, RH ;
Condeelis, J .
CURRENT BIOLOGY, 2004, 14 (08) :697-703
[58]   Scar, a WASp-related protein, activates nucleation of actin filaments by the Arp2/3 complex [J].
Machesky, LM ;
Mullins, RD ;
Higgs, HN ;
Kaiser, DA ;
Blanchoin, L ;
May, RC ;
Hall, ME ;
Pollard, TD .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (07) :3739-3744
[59]   PURIFICATION OF A CORTICAL COMPLEX CONTAINING 2 UNCONVENTIONAL ACTINS FROM ACANTHAMOEBA BY AFFINITY-CHROMATOGRAPHY ON PROFILIN-AGAROSE [J].
MACHESKY, LM ;
ATKINSON, SJ ;
AMPE, C ;
VANDEKERCKHOVE, J ;
POLLARD, TD .
JOURNAL OF CELL BIOLOGY, 1994, 127 (01) :107-115
[60]   Scar1 and the related Wiskott-Aldrich syndrome protein, WASP, regulate the actin cytoskeleton through the Arp2/3 complex [J].
Machesky, LM ;
Insall, RH .
CURRENT BIOLOGY, 1998, 8 (25) :1347-1356