共 115 条
Arp2/3 and scar: Plants move to the fore
被引:63
作者:

Deeks, MJ
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机构:
Univ Durham, Sch Biol & Biomed Sci, Integrat Cell Biol Lab, Durham DH1 3LE, England Univ Durham, Sch Biol & Biomed Sci, Integrat Cell Biol Lab, Durham DH1 3LE, England

Hussey, PJ
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机构:
Univ Durham, Sch Biol & Biomed Sci, Integrat Cell Biol Lab, Durham DH1 3LE, England Univ Durham, Sch Biol & Biomed Sci, Integrat Cell Biol Lab, Durham DH1 3LE, England
机构:
[1] Univ Durham, Sch Biol & Biomed Sci, Integrat Cell Biol Lab, Durham DH1 3LE, England
基金:
英国生物技术与生命科学研究理事会;
关键词:
D O I:
10.1038/nrm1765
中图分类号:
Q2 [细胞生物学];
学科分类号:
071009 ;
090102 ;
摘要:
The actin-nucleating Arp2/3 complex is essential for life in yeast and animals, but not in plants, in which mutants of Arp2/3 complex components show relatively minor developmental abnormalities. Animal cells control the activity of the Arp2/3 complex through the suppressor of cyclic AMP receptor ( SCAR) complex to achieve cell motility. Amazingly, plants have also retained the SCAR cell-motility pathway, and now provide a unique model for the study of new aspects of SCAR function in the absence of cell motility.
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页码:954 / 964
页数:11
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