Fluorescent composite scaffolds made of nanodiamonds/polycaprolactone

被引：13

作者：

Cao, Li ^{[1
]}

Hou, Yanwen ^{[1
]}

Lafdi, Khalid ^{[1
]}

Urmey, Kirk

机构：

[1] Univ Dayton, Dept Chem & Mat Engn, Dayton, OH 45469 USA

来源：

CHEMICAL PHYSICS LETTERS | 2015年 / 641卷

关键词：

DRUG-DELIVERY; TISSUE; DESIGN; NANODIAMOND; BONE; MELT; MICROFIBERS; ASSEMBLIES; NANOFIBERS; DIAMOND;

D O I：

10.1016/j.cplett.2015.10.037

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Polycaprolactone (PCL) has been widely studied for biological applications. Biodegradable PCL fibrous scaffold can work as an appropriate substrate for tissue regeneration. In this letter, fluorescent nanodiamonds (FNDs) were prepared after surface passivation with octadecylamine. The FNDs were then mixed with PCL polymer and subsequently electrospun into FNDs/PCL fibrous scaffolds. The obtained scaffolds not only exhibited photoluminescence, but also showed reinforced mechanical strength. Toxicity study indicated FNDs/PCL scaffolds were nontoxic. This biocompatible fluorescent composite fibrous scaffold can support in vitro cell growth and also has the potential to act as an optical probe for tissue engineering application in vitro and in vivo. (C) 2015 Elsevier B.V. All rights reserved.

引用

页码：123 / 128

页数：6

共 43 条

[1] Use of electrospinning technique for biomedical applications [J].

Agarwal, Seema ;

Wendorff, Joachim H. ;

Greiner, Andreas .

POLYMER, 2008, 49 (26) :5603-5621

[2]

Agrawal CM, 2001, J BIOMED MATER RES, V55, P141, DOI 10.1002/1097-4636(200105)55:2<141::AID-JBM1000>3.0.CO

[3]

2-J

[4] Nanodiamond-Polymer Composite Fibers and Coatings [J].

Behler, Kristopher D. ;

Stravato, Antonella ;

Mochalin, Vadym ;

Korneva, Guzeliya ;

Yushin, Gleb ;

Gogotsi, Yury .

ACS NANO, 2009, 3 (02) :363-369

[5] Fluorescent nanodiamonds derived from HPHT with a size of less than 10 nm [J].

Boudou, Jean-Paul ;

Tisler, Julia ;

Reuter, Rolf ;

Thorel, Alain ;

Curmi, Patrick A. ;

Jelezko, Fedor ;

Wrachtrup, Joerg .

[6] High yield fabrication of fluorescent nanodiamonds [J].

Boudou, Jean-Paul ;

Curmi, Patrick A. ;

Jelezko, Fedor ;

Wrachtrup, Joerg ;

Aubert, Pascal ;

Sennour, Mohamed ;

Balasubramanian, Gopalakrischnan ;

Reuter, Rolf ;

Thorel, Alain ;

Gaffet, Eric .

NANOTECHNOLOGY, 2009, 20 (23)

[7] Design and Fabrication of Tubular Scaffolds via Direct Writing in a Melt Electrospinning Mode [J].

Brown, Toby D. ;

Slotosch, Anna ;

Thibaudeau, Laure ;

Taubenberger, Anna ;

Loessner, Daniela ;

Vaquette, Cedryck ;

Dalton, Paul D. ;

Hutmacher, Dietmar W. .

BIOINTERPHASES, 2012, 7 (1-4) :1-16

[8] Direct Writing By Way of Melt Electrospinning [J].

Brown, Toby D. ;

Dalton, Paul D. ;

Hutmacher, Dietmar W. .

ADVANCED MATERIALS, 2011, 23 (47) :5651-+

[9]

Burleson T., 2009, JAMME, V37, P258

[10] Carbon dots for multiphoton bioimaging [J].

Cao, Li ;

Wang, Xin ;

Meziani, Mohammed J. ;

Lu, Fushen ;

Wang, Haifang ;

Luo, Pengju G. ;

Lin, Yi ;

Harruff, Barbara A. ;

Veca, L. Monica ;

Murray, Davoy ;

Xie, Su-Yuan ;

Sun, Ya-Ping .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2007, 129 (37) :11318-+

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