Development and Validation of the Individual Burden of Illness Index for Major Depressive Disorder (IBI-D)

被引：21

作者：

IsHak, Waguih William ^{[1
,2
]}

Greenberg, Jared Matt ^{[2
,3
]}

Saah, Tammy ^{[4
]}

Mobaraki, Shakiba ^{[2
]}

Fakhry, Hala ^{[5
]}

Wu, Qian ^{[6
]}

Ngor, Eunis ^{[6
]}

Yu, Fei ^{[6
]}

Cohen, Robert M. ^{[7
,8
]}

机构：

[1] Univ Calif Los Angeles, Dept Psychiat & Behav Neurosci, Cedars Sinai Med Ctr, Los Angeles, CA 90048 USA

[2] Univ Calif Los Angeles, David Geffen Sch Med, Los Angeles, CA 90048 USA

[3] Univ So Calif, Keck Sch Med, Los Angeles, CA 90033 USA

[4] Emory Univ, Atlanta, GA 30322 USA

[5] Cairo Univ, Fac Med, Dept Psychiat, Cairo, Egypt

[6] Univ Calif Los Angeles, Sch Publ Hlth, Los Angeles, CA 90048 USA

[7] Univ Calif Los Angeles, Dept Psychiat & Biobehav Sci, Los Angeles, CA 90048 USA

[8] Cedars Sinai Med Ctr, S Mark Taper Fdn Imaging Dept, Los Angeles, CA 90048 USA

来源：

ADMINISTRATION AND POLICY IN MENTAL HEALTH AND MENTAL HEALTH SERVICES RESEARCH | 2013年 / 40卷 / 02期

关键词：

Burden of illness; Major depressive disorder; Major depression; Outcome measurement; Quality of life; STAR*D; QUALITY-OF-LIFE; SEQUENCED TREATMENT ALTERNATIVES; STAR-ASTERISK-D; DISABILITY; REMISSION; OUTPATIENTS; IMPAIRMENT; RATIONALE; INVENTORY; DISEASE;

D O I：

10.1007/s10488-011-0376-6

中图分类号：

R19 [保健组织与事业（卫生事业管理）];

学科分类号：

摘要：

This study aims at developing a single numerical measure that represents a depressed patient's individual burden of illness. An exploratory study examined depressed outpatients (n = 317) followed by a hypothesis confirmatory study using the NIMH STAR*D trial (n = 2,967). Eigenvalues/eigenvectors were obtained from the Principal Component Analyses of patient-reported measures of symptom severity, functioning, and quality of life. The study shows that a single principal component labeled as the Individual Burden of Illness Index for Depression (IBI-D) accounts for the vast majority of the variance contained in these three measures providing a numerical z score for clinicians and investigators to determine an individual's burden of illness, relative to other depressed patients.

引用

页码：76 / 86

页数：11

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