Clinico-pathological correlation of UBE2C alterations in colorectal carcinoma and efficacy of UBE2C inhibition by proteosome inhibitor as a viable therapeutic target

被引:0
作者
Bu, Rong [1 ]
Bavi, Prashant [1 ]
Hussain, Azhar R. [1 ]
Jehan, Zeenath [1 ]
Abubaker, Jehad [1 ]
Al-Sanea, Nasser A. [1 ]
Abduljabbar, Alaa S. [1 ]
Ashari, Luai H. [1 ]
Al-Homoud, Samar J. [1 ]
Al-Dayel, Fouad [1 ]
George, Thara [1 ]
Qadri, Zeeshan [1 ]
Hassan, Nurul [1 ]
Prabhakaran, Sarita E. [1 ]
Ahmed, Magbool [1 ]
Uddin, Shahab [1 ]
Al-Kuraya, Khawla S. [1 ]
机构
[1] King Faisal Specialist Hosp & Res Ctr, Riyadh 11211, Saudi Arabia
关键词
D O I
10.1158/1538-7445.AM2011-2980
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
2980
引用
收藏
页数:1
相关论文
共 50 条
[21]   UBE2S and UBE2C confer a poor prognosis to breast cancer via downregulation of Numb [J].
Guo, Yanjing ;
Chen, Xinyu ;
Zhang, Xiaowei ;
Hu, Xichun .
FRONTIERS IN ONCOLOGY, 2023, 13
[22]   UBE2C is involved in the functions of ECRG4 on esophageal squamous cell carcinoma [J].
Li, Linwei ;
Li, Xiaoyan ;
Wang, Wenyu ;
Gao, Tianhui ;
Shi, Zuxuan .
BIOMEDICINE & PHARMACOTHERAPY, 2018, 98 :201-206
[23]   Nobiletin inhibits cell proliferation and invasion via suppression of UBE2C in hepatocellular carcinoma [J].
Su, Jinzhan ;
Fan, Shufeng ;
Su, Dongying ;
Li, Miaoer ;
Song, Xia .
SCIENCEASIA, 2024, 50 (05)
[24]   Comprehensive analysis of UBE2C expression and its potential roles and mechanisms in hepatocellular carcinoma [J].
Li, Xiao ;
Ma, Zhaosheng ;
Mei, Linhang .
AGING-US, 2023, 15 (15) :7397-7407
[25]   The activation of the Notch signaling pathway by UBE2C promotes the proliferation and metastasis of hepatocellular carcinoma [J].
Zhan, Ping ;
Lu, Yuyan ;
Lu, Jing ;
Cheng, Yizhe ;
Luo, Changhong ;
Yang, Fan ;
Xi, Wenqing ;
Wang, Jinzhu ;
Cen, Xuesong ;
Wang, Fuqiang ;
Xie, Chengrong ;
Yin, Zhenyu .
SCIENTIFIC REPORTS, 2024, 14 (01)
[26]   UBE2C expression is elevated in hepatoblastoma and correlates with inferior patient survival [J].
Nousiainen, Ruth ;
Eloranta, Katja ;
Isoaho, Noora ;
Cairo, Stefano ;
Wilson, David B. ;
Heikinheimo, Markku ;
Pihlajoki, Marjut .
FRONTIERS IN GENETICS, 2023, 14
[27]   Fabrication of an immunosensor for quantitative detection of breast cancer biomarker UBE2C [J].
Jayanthi, V. S. P. K. Sankara Aditya ;
Das, Asim Bikas ;
Saxena, Urmila .
RSC ADVANCES, 2019, 9 (29) :16738-16745
[28]   UBE2C is a diagnosis and therapeutic biomarker involved in immune infiltration of cancers including lung adenocarcinoma [J].
Cai, Daxia ;
Tian, Feng ;
Wu, Minhua ;
Tu, Jianfei ;
Wang, Yonghui .
JOURNAL OF CANCER, 2024, 15 (06) :1701-1717
[29]   Overexpression of UBE2C correlates with poor prognosis in gastric cancer patients [J].
Zhang, H. -Q. ;
Zhao, G. ;
Ke, B. ;
Ma, G. ;
Liu, G. -L. ;
Liang, H. ;
Liu, L. -R. ;
Hao, X. -S. .
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, 2018, 22 (06) :1665-1671
[30]   High expression of ubiquitin-conjugating enzyme 2C (UBE2C) correlates with nasopharyngeal carcinoma progression [J].
Shen, Zhihua ;
Jiang, Xiaofan ;
Zeng, Chao ;
Zheng, Shaojiang ;
Luo, Botao ;
Zeng, Yumei ;
Ding, Ranran ;
Jiang, Hanguo ;
He, Qiyi ;
Guo, Junli ;
Jie, Wei .
BMC CANCER, 2013, 13