Trichromatic-emission and dual-ratio semiconducting polymer dots as fluorescent probe for simultaneous quantification of Cu2+and pHin vitroandin vivo

被引:22
作者
Zhang, Qiang [1 ]
Sun, Junyong [1 ]
Zhang, Rongchao [1 ]
Chen, Xueli [1 ]
Chen, Ningning [1 ]
Gao, Feng [1 ]
机构
[1] Anhui Normal Univ, Lab Functionalized Mol Solids, Minist Educ,Coll Chem & Mat Sci, Anhui Key Lab Chemo Biosensing,Lab Biosensing & B, Wuhu 241002, Peoples R China
关键词
ENERGY-TRANSFER; DYSFUNCTION;
D O I
10.1039/d0cc01811b
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Novel dual-ratio semiconducting polymer dots (Pdots) with trichromatic-emission in the red, green and blue primary-color regions, are designed as lysosome-targeting nanoprobes for the simultaneous detection and multicolor imaging of pH and Cu(2+)in HeLa cells and zebrafish without cross-interference.
引用
收藏
页码:8647 / 8650
页数:4
相关论文
共 23 条
  • [1] Copper Ion Fluorescent Probe Based on Zr-MOFs Composite Material
    Chen, Jing
    Chen, Haiyong
    Wang, Tiansheng
    Li, Jinfang
    Wang, Jing
    Lu, Xiaoquan
    [J]. ANALYTICAL CHEMISTRY, 2019, 91 (07) : 4331 - 4336
  • [2] A Trichromatic and White-Light-Emitting MOF Composite for Multi-Dimensional and Multi-Response Ratiometric Luminescent Sensing
    Dai, Yue
    Zhang, Jian-Jun
    Liu, Shu-Qin
    Zhou, Huajun
    Sun, Ying-Ji
    Pan, Yu-Zhen
    Ni, Jun
    Yang, Jing-Si
    [J]. CHEMISTRY-A EUROPEAN JOURNAL, 2018, 24 (38) : 9555 - 9564
  • [3] A tumor-targeting and lysosome-specific two-photon fluorescent probe for imaging pH changes in living cells
    Dong, Baoli
    Song, Xuezhen
    Kong, Xiuqi
    Wang, Chao
    Zhang, Nan
    Lin, Weiying
    [J]. JOURNAL OF MATERIALS CHEMISTRY B, 2017, 5 (05) : 988 - 995
  • [4] Dysfunction of endocytic and autophagic pathways in a lysosomal storage disease
    Fukuda, T
    Ewan, L
    Bauer, M
    Mattaliano, RJ
    Zaal, K
    Ralston, E
    Plotz, PH
    Raben, N
    [J]. ANNALS OF NEUROLOGY, 2006, 59 (04) : 700 - 708
  • [5] Copper signaling in the mammalian nervous system: Synaptic effects
    Gaier, E. D.
    Eipper, B. A.
    Mains, R. E.
    [J]. JOURNAL OF NEUROSCIENCE RESEARCH, 2013, 91 (01) : 2 - 19
  • [6] Fluorescent probes for organelle-targeted bioactive species imaging
    Gao, Peng
    Pan, Wei
    Li, Na
    Tang, Bo
    [J]. CHEMICAL SCIENCE, 2019, 10 (24) : 6035 - 6071
  • [7] A pH-responsive nanoprobe for turn-on 19F-magnetic resonance imaging
    Guo, Chang
    Xu, Suying
    Arshad, Anila
    Wang, Leyu
    [J]. CHEMICAL COMMUNICATIONS, 2018, 54 (70) : 9853 - 9856
  • [8] Single Probe for Imaging and Biosensing of pH, Cu2+ Ions, and pH/Cu2+ in Live Cells with Ratiometric Fluorescence Signals
    Han, Yingying
    Ding, Changqin
    Zhou, Jie
    Tian, Yang
    [J]. ANALYTICAL CHEMISTRY, 2015, 87 (10) : 5333 - 5339
  • [9] Enhancing singlet oxygen generation in semiconducting polymer nanoparticles through fluorescence resonance energy transfer for tumor treatment
    Jiang, Jiayang
    Qian, Yuanyuan
    Xu, Zihan
    Lv, Zhuang
    Tao, Peng
    Xie, Mingjuan
    Liu, Shujuan
    Huang, Wei
    Zhao, Qiang
    [J]. CHEMICAL SCIENCE, 2019, 10 (19) : 5085 - 5094
  • [10] ATP7A-related copper transport diseases-emerging concepts and future trends
    Kaler, Stephen G.
    [J]. NATURE REVIEWS NEUROLOGY, 2011, 7 (01) : 15 - 29