Closing the Loop

被引：2

作者：

Nimri, Revital ^{[1
]}

Audon, Pearl ^{[2
]}

Pinsker, Jordan E. ^{[2
]}

Dassau, Eyal ^{[2
,3
]}

机构：

[1] Schneider Childrens Med Ctr Israel, Natl Ctr Childhood Diabet, Jesse Z & Sara Lea Shafer Inst Endocrinol & Diabe, Petah Tiqwa, Israel

[2] Sansum Diabet Res Inst, Santa Barbara, CA USA

[3] Harvard Univ, Harvard John A Paulson Sch Engn & Appl Sci, Cambridge, MA 02138 USA

来源：

DIABETES TECHNOLOGY & THERAPEUTICS | 2018年 / 20卷

关键词：

ARTIFICIAL PANCREAS; INSULIN DELIVERY; GLUCOSE CONTROL; ADOLESCENTS; OVERNIGHT; CHILDREN; PUMP;

D O I：

10.1089/dia.2018.2504

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This year's articles showed the true potential of AP in the outpatient setting. The next step is to take the systems studied and subject them to rigorous randomized controlled outpatient home use trials. As shown in a recent systematic review and meta-analysis, there remain a number of unanswered questions, particularly in studies with remote monitoring that may lead to improved reporting of results (12). Future long-term studies will prove the efficacy of single- and dual-hormone systems, and it is only through rigorous, structured controlled trials in the anticipated real-world home use setting (i.e., without remote monitoring) that investigators will be able to improve AP devices to optimize outcomes. The greatest breakthrough and important milestone in the pathway of implementation of closed-loop systems to regular diabetes treatment was recently made by the FDA approval of the first Medtronic hybrid closed-loop system. Ultimately, patients with diabetes will benefit greatly from the number of systems under development by commercial entities. © Mary Ann Liebert, Inc.

引用

页码：S41 / S54

页数：14

共 12 条

[1] Intraperitoneal insulin delivery provides superior glycaemic regulation to subcutaneous insulin delivery in model predictive control-based fully-automated artificial pancreas in patients with type 1 diabetes: a pilot study [J].

Dassau, Eyal ;

Renard, Eric ;

Place, Jerome ;

Farret, Anne ;

Pelletier, Marie-Jose ;

Lee, Justin ;

Huyett, Lauren M. ;

Chakrabarty, Ankush ;

Doyle, Francis J., III ;

Zisser, Howard C. .

DIABETES OBESITY & METABOLISM, 2017, 19 (12) :1698-1705

[2] Home use of a bihormonal bionic pancreas versus insulin pump therapy in adults with type 1 diabetes: a multicentre randomised crossover trial [J].

El-Khatib, Firas H. ;

Balliro, Courtney ;

Hillard, Mallory A. ;

Magyar, Kendra L. ;

Ekhlaspour, Laya ;

Sinha, Manasi ;

Mondesir, Debbie ;

Esmaeili, Aryan ;

Hartigan, Celia ;

Thompson, Michael J. ;

Malkani, Samir ;

Lock, J. Paul ;

Harlan, David M. ;

Clinton, Paula ;

Frank, Eliana ;

Wilson, Darrell M. ;

DeSalvo, Daniel ;

Norlander, Lisa ;

Ly, Trang ;

Buckingham, Bruce A. ;

Diner, Jamie ;

Dezube, Milana ;

Young, Laura A. ;

Goley, April ;

Kirkman, M. Sue ;

Buse, John B. ;

Zheng, Hui ;

Selagamsetty, Rajendranath R. ;

Damiano, Edward R. ;

Russell, Steven J. .

LANCET, 2017, 389 (10067) :369-380

[3] Experiences of closed-loop insulin delivery among pregnant women with Type 1 diabetes [J].

Farrington, C. ;

Stewart, Z. A. ;

Barnard, K. ;

Hovorka, R. ;

Murphy, H. R. .

DIABETIC MEDICINE, 2017, 34 (10) :1461-1469

[4] Outpatient overnight glucose control with dual-hormone artificial pancreas, single-hormone artificial pancreas, or conventional insulin pump therapy in children and adolescents with type 1 diabetes: an open-label, randomised controlled trial [J].

Haidar, Ahmad ;

Legault, Laurent ;

Matteau-Pelletier, Laurence ;

Messier, Virginie ;

Dallaire, Maryse ;

Ladouceur, Martin ;

Rabasa-Lhoret, Remi .

LANCET DIABETES & ENDOCRINOLOGY, 2015, 3 (08) :595-604

[5] Outpatient Closed-Loop Control with Unannounced Moderate Exercise in Adolescents Using Zone Model Predictive Control [J].

Huyett, Lauren M. ;

Ly, Trang T. ;

Forlenza, Gregory P. ;

Reuschel-DiVirgilio, Suzette ;

Messer, Laurel H. ;

Wadwa, R. Paul ;

Gondhalekar, Ravi ;

Doyle, Francis J., III ;

Pinsker, Jordan E. ;

Maahs, David M. ;

Buckingham, Bruce A. ;

Dassau, Eyal .

DIABETES TECHNOLOGY & THERAPEUTICS, 2017, 19 (06) :331-339

[6]

Kitagawa H, 2016, ANTICANCER RES, V36, P4063

[7] Closed- Loop Artificial Pancreas Systems: Physiological Input to Enhance Next- Generation Devices [J].

Kudva, Yogish C. ;

Carter, Rickey E. ;

Cobelli, Claudio ;

Basu, Rita ;

Basu, Ananda .

DIABETES CARE, 2014, 37 (05) :1184-1190

[8] Strict blood glucose control by an artificial endocrine pancreas during hepatectomy may prevent postoperative acute kidney injury [J].

Mita, Naoji ;

Kawahito, Shinji ;

Soga, Tomohiro ;

Takaishi, Kazumi ;

Kitahata, Hiroshi ;

Matsuhisa, Munehide ;

Shimada, Mitsuo ;

Kinoshita, Hiroyuki ;

Tsutsumi, Yasuo M. ;

Tanaka, Katsuya .

JOURNAL OF ARTIFICIAL ORGANS, 2017, 20 (01) :76-83

[9] Comparison between a novel and conventional artificial pancreas for perioperative glycemic control using a closed-loop system [J].

Namikawa, Tsutomu ;

Munekage, Masaya ;

Kitagawa, Hiroyuki ;

Yatabe, Tomoaki ;

Maeda, Hiromichi ;

Tsukamoto, Yuuki ;

Hirano, Kenichi ;

Asano, Takuji ;

Kinoshita, Yoshihiko ;

Hanazaki, Kazuhiro .

JOURNAL OF ARTIFICIAL ORGANS, 2017, 20 (01) :84-90

[10] Glycemia, Treatment Satisfaction, Cognition, and Sleep Quality in Adults and Adolescents with Type 1 Diabetes When Using a Closed-Loop System Overnight Versus Sensor-Augmented Pump with Low-Glucose Suspend Function: A Randomized Crossover Study [J].

Sharifi, Amin ;

De Bock, Martin I. ;

Jayawardene, Dilshani ;

Loh, Margaret M. ;

Horsburgh, Jodie C. ;

Berthold, Carolyn L. ;

Paramalingam, Nirubasini ;

Bach, Leon A. ;

Colman, Peter G. ;

Davis, Elizabeth A. ;

Grosman, Benyamin ;

Hendrieckx, Christel ;

Jenkins, Alicia J. ;

Kumareswaran, Kavita ;

Kurtz, Natalie ;

Kyoong, Andrew ;

MacIsaac, Richard J. ;

Speight, Jane ;

Trawley, Steven ;

Ward, Glenn M. ;

Roy, Anirban ;

Jones, Timothy W. ;

O'Neal, David N. .

DIABETES TECHNOLOGY & THERAPEUTICS, 2016, 18 (12) :772-+

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