Calcified plaque: Measurement of area at thin-section flat-panel CT and 64-section multidetector CT and comparison with histopathologic findings

被引:55
作者
Sarwar, Ammar [1 ]
Rieber, Johannes [1 ]
Mooyaart, Eline A. Q. [1 ]
Seneviratne, Sujith K. [1 ]
Houser, Stuart L. [1 ]
Bamberg, Fabian [1 ]
Raffel, O. Christopher [1 ]
Gupta, Rajiv [1 ]
Kalra, Mannudeep K. [1 ]
Pien, Homer [1 ]
Lee, Hang [1 ]
Brady, Thomas J. [1 ]
Hoffmann, Udo [1 ]
机构
[1] Massachusetts Gen Hosp, Cardiac MR PET CT Program, Boston, MA 02114 USA
关键词
D O I
10.1148/radiol.2483072003
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
The purpose of this study was to assess the blooming artifacts in ex vivo coronary arteries at multidetector computed tomography (CT) and flat-panel-volume CT by comparing measured areas of calcified plaque with respect to the reference standard of histopathologic findings. Three ex vivo hearts were scanned with multidetector CT and flat-panel-volume CT after institutional review board approval. The area of calcified plaque was measured at histopathologic examination, multidetector CT, and flat-panel volume CT. The plaque area was overestimated at multidetector CT by 400% (4.61/1.15) on average, and the predicted difference between the measurements was significant (3.46 mm(2), P = .018). The average overestimation of plaque area at flat-panel-volume CT was twofold (214% [2.18/1.02]), and the predicted difference was smaller (1.16 mm(2), P = .08). The extent of the blooming artifact in visualizing calcified coronary plaque is reduced by using flat-panel-volume CT. (c) RSNA, 2008.
引用
收藏
页码:301 / 306
页数:6
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