Phase Diagrams of the Aqueous Two-Phase Systems of Poly(ethylene glycol)/Sodium Polyacrylate/Salts

被引：54

作者：

Johansson, Hans-Olof ^{[1
]}

Feitosa, Eloi ^{[2
]}

Pessoa Junior, Adalberto ^{[3
]}

机构：

[1] Lund Univ, Dept Biochem & Struct Biol, SE-22100 Lund, Sweden

[2] Sao Paulo State Univ, Dept Phys, UNESP, IBILCE, BR-15054000 Sao Jose Do Rio Preto, Brazil

[3] Univ Sao Paulo, Dept Biochem & Pharmaceut Technol, BR-05508000 Sao Paulo, Brazil

来源：

POLYMERS | 2011年 / 3卷 / 01期

基金：

巴西圣保罗研究基金会;

关键词：

poly(ethylene glycol); sodium polyacrylate; ATPS; Flory-Huggins theory; phase diagram; hydrophobic ions; POLY(ACRYLIC ACID); SEPARATION; PROTEIN; PARTITION; SALTS; IONS; PH;

D O I：

10.3390/polym3010587

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Aqueous two-phase systems consisting of polyethylene glycol (PEG), sodium polyacrylate (NaPAA), and a salt have been studied. The effects of the polymer size, salt type (NaCl, Na2SO4, sodium adipate and sodium azelate) and salt concentrations on the position of the binodal curve were investigated. The investigated PEG molecules had a molar mass of 2,000 to 8,000 g/mol, while that of NaPAA was 8,000 g/mol. Experimental phase diagrams, and tie lines and calculated phase diagrams, based on Flory-Huggins theory of polymer solutions are presented. Due to strong enthalpic and entropic balancing forces, the hydrophobicity of the added salt has a strong influence on the position of the binodal, which could be reproduced by model calculations.

引用

页码：587 / 601

页数：15

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