Implication of Conjugated Linoleic Acid (CLA) in Human Health

被引：300

作者：

Dilzer, Allison ^{[1
]}

Park, Yeonhwa ^{[1
]}

机构：

[1] Univ Massachusetts, Dept Food Sci, Amherst, MA 01003 USA

来源：

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION | 2012年 / 52卷 / 06期

关键词：

conjugated linoleic acid; CLA; trans fatty acids; obesity; cardiovascular diseases; cancer; bone; BODY-FAT MASS; TRANSEPITHELIAL CALCIUM-TRANSPORT; C-REACTIVE PROTEIN; MODERATELY OVERWEIGHT SUBJECTS; POSTMENOPAUSAL BREAST-CANCER; RATS FED N-6; LIPID-PEROXIDATION; ADIPOSE-TISSUE; INSULIN SENSITIVITY; DIETARY SUPPLEMENTATION;

D O I：

10.1080/10408398.2010.501409

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

Conjugated linoleic acid (CLA) has drawn significant attention in the last two decades for its variety of biologically beneficial effects. CLA reduces body fat, cardiovascular diseases and cancer, and modulates immune and inflammatory responses as well as improves bone mass. It has been suggested that the overall effects of CLA are the results of interactions between two major isomers, cis-9,trans-11 and trans-10,cis-12. This review will primarily focus on current CLA publications involving humans, which are also summarized in the tables. Along with a number of beneficial effects of CLA, there are safety considerations for CLA supplementation in humans, which include effects on liver functions, milk fat depression, glucose metabolism, and oxidative stresses.

引用

页码：488 / 513

页数：26

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