Prevention of Acute Kidney Injury

被引：19
作者：
Kullmar, Mira [1 ]
Zarbock, Alexander [1 ]
Engelman, Daniel T. [2 ,3 ]
Chatterjee, Subhasis [4 ,5 ]
Wagner, Nana-Maria [1 ]
机构：
[1] Univ Munster, Dept Anesthesiol Intens Care & Pain Med, Albert Schweitzer Campus 1,Bldg A1, D-48149 Munster, Germany
[2] Baystate Hlth, Heart & Vasc Program, 759 Chestnut St, Springfield, MA 01199 USA
[3] Univ Massachusetts, Med Sch Baystate, 759 Chestnut St, Springfield, MA 01199 USA
[4] Baylor Coll Med, Dept Surg, One Baylor Plaza,MS BCM 390, Houston, TX 77030 USA
[5] Texas Heart Inst, Div Cardiovasc Surg, Houston, TX 77025 USA
来源：
CRITICAL CARE CLINICS | 2020年 / 36卷 / 04期
关键词：
Acute kidney injury (AKI); Cardiac surgery; KDIGO bundles; Renal biomarkers; Prevention of acute kidney injury (AKI); GELATINASE-ASSOCIATED LIPOCALIN; RENAL-REPLACEMENT THERAPY; BYPASS GRAFT-SURGERY; CYCLE ARREST BIOMARKERS; MEAN ARTERIAL-PRESSURE; INTENSIVE-CARE-UNIT; LONG-TERM MORTALITY; CARDIAC-SURGERY; CARDIOPULMONARY BYPASS; INSULIN THERAPY;
D O I：
10.1016/j.ccc.2020.07.002
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
Cardiac surgery–associated acute kidney injury (CSA-AKI) is a common complication after cardiac surgery and associated with a worse outcome. The pathogenesis of CSA-AKI is complex and multifactorial. Therapeutic options for severe CSA-AKI are limited to renal replacement therapy constituting a supportive measure. Therefore, risk identification, prevention, and early diagnosis are of utmost importance to improve patient outcomes. This review aims to provide an overview of the diagnosis, pathophysiologic mechanisms, and risk factors of CSA-AKI and delineates the strategies for AKI prevention available to improve patient outcomes after cardiac surgery. © 2020 Elsevier Inc.
引用
收藏
页码：691 / 704
页数：14
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