Cardiorenal Syndrome: A Cardiologist's Perspective of Pathophysiology

被引:32
作者
Anand, Inder S. [1 ,2 ]
机构
[1] Vet Affairs Med Ctr, Dept Med, Minneapolis, MN 55417 USA
[2] Univ Minnesota, Div Cardiovasc Med, Minneapolis, MN USA
来源
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY | 2013年 / 8卷 / 10期
关键词
DECOMPENSATED HEART-FAILURE; WORSENING RENAL-FUNCTION; PLASMA HORMONES; BODY-WATER; VENOUS-PRESSURE; HOSPITALIZED-PATIENTS; CONSENSUS CONFERENCE; PROSPECTIVE COHORT; CARDIAC-FAILURE; BROAD-SPECTRUM;
D O I
10.2215/CJN.04090413
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
The cardiorenal syndrome has recently been defined as disorders of the heart and kidney whereby acute or chronic dysfunction in one organ may induce acute or chronic dysfunction of the other. The syndrome is extremely common and independently associated with poor clinical outcomes. However, no pharmacological therapy has been shown to improve its outcomes. Unfortunately, the mechanisms that initiate the development of renal dysfunction in heart failure are still debated. This review tries to clarify some of the misunderstanding regarding the principle hemodynamic factors that drive the kidneys to retain salt and water.
引用
收藏
页码:1800 / 1807
页数:8
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