Islet Cell Transplantation and Alternative Therapies

被引:2
作者
Hatipoglu, Betul [1 ]
机构
[1] Cleveland Clin, Endocrinol & Metab Inst, 9500 Euclid Ave,F20, Cleveland, OH 44195 USA
关键词
Pancreas transplantation; Islet transplantation; Type; 1; diabetes; Beta cells; TYPE-1; DIABETES-MELLITUS; INSULIN INDEPENDENCE; BETA-CELLS; PANCREAS; TRIAL; XENOTRANSPLANTATION; PREVENTION; ANTI-LFA-1; RECIPIENTS; REVERSAL;
D O I
10.1016/j.ecl.2016.06.004
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Even though type 2 diabetes rates plateaued, type 1 diabetes continues to increase. Pancreas transplantation is a treatment modality for patients who suffer hypoglycemic unawareness or complications from diabetes. Islet cell transplantation success rates have improved with modification and advances in isolation, transplantation, and new immunosuppression regimens. The new cell sources as well as delivery ways are explored and being tested in human trials.
引用
收藏
页码:923 / +
页数:10
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